Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 跨膜蛋白
  4. Recombinant TWiK family of potassium channels protein 7 (twk-7)

Recombinant TWiK family of potassium channels protein 7 (twk-7)

  • 中文名稱：
    秀麗隱桿線蟲twk-7重組蛋白
  • 貨號(hào)：
    CSB-CF341529CXY
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
    twk-7
  • Uniprot No.：
  • 別名：
    twk-7; twk-8; F22B7.7; TWiK family of potassium channels protein 7
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-557
  • 氨基酸序列
    MTSSSRGYQRVDSSGDGGSLLMEEEGDNPHEALLHRNNDDYASTYHHVGVEYDSYEELER HEMDDRVTEIPEGFHRRQRRNLIYGDDVATDEELRVLRREALFGEEVTRAGLGRAEYYED SHLIHSCDKSGHEDIDDESDDESKDEDEEEEETGIRKFAKLVLPHVALVLLTCTYTVIGA LIFYSVEQPHEQMMKEQQLKLIYTRQNEFVDDLIRLAAGNETKRYEWESLAERHMHNMSD QLFVAFEKYFLTSNEVKKNAATETWTFSSSIFFAVTVVTTIGYGNPVPVTNIGRIWCILF SLLGIPLTLVTIADLGKFLSEHLVWLYGNYLKLKYLILSRHRKERREHVCEHCHSHGMGH DMNIEEKRIPAFLVLAILIVYTAFGGVLMSKLEPWSFFTSFYWSFITMTTVGFGDLMPRR DGYMYIILLYIILGLAITTMCIDLVGVQYIRKIHYFGRKIQDARSALAVVGGKVVLVSEL YANLMQKRARNMSREAFIVENLYVSKHIIPFIPTDIRCIRYIDQTADAATISTSSSAIDM QSCRFCHSRYSLNRAFK
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. we identified TWK-7 as a putative downstream target of the GalphaS-KIN-1/PKA pathway at the level of the gamma-aminobutyric acid (GABA)ergic D-type motor neurons. Due to this epistatic interaction, we suggest that KIN-1/PKA and TWK-7 may share a common pathway that is probably involved in the modulation of both locomotor activity and locomotion behavior during forward crawling. PMID: 28341653
    2. we suggest that TWK-7 activity might represent a means to modulate a complex locomotion behavior at the level of certain types of motor neurons. PMID: 27535928
  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Two pore domain potassium channel (TC 1.A.1.8) family
  • 數(shù)據(jù)庫鏈接：

    KEGG: cel:CELE_F22B7.7

    STRING: 6239.F22B7.7

    UniGene: Cel.17711