AURKB
AURKB，即極光激酶B，別名AIK2、AIM1、ARK2、AurB、IPL1、STK5、AIM-1、ARK-2、STK-1、STK12、PPP1R48、aurkb-sv1、aurkb-sv2等。它來源于細(xì)胞內(nèi)的基因編碼，是極光激酶家族的一員。AURKB在細(xì)胞有絲分裂過程中發(fā)揮關(guān)鍵作用，通過磷酸化多種蛋白質(zhì)底物來調(diào)控染色體的凝聚、紡錘體的組裝以及細(xì)胞周期的正確進(jìn)展。其作用機(jī)制確保了細(xì)胞分裂的準(zhǔn)確性和時序性。在生物學(xué)上，AURKB的異常表達(dá)與多種癌癥的發(fā)生和發(fā)展密切相關(guān)，因此成為癌癥研究中的熱點。
熱銷產(chǎn)品
AURKB Antibody (CSB-PA002458EA01HU)
驗證數(shù)據(jù)
Immunofluorescence staining of Hela cells with CSB-PA002458EA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA002458EA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA002458EA01HU at dilution of 1:100
AURKB Antibodies
AURKB for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA002458EA01HU | AURKB Antibody | Human | ELISA, IHC, IF |
| CSB-PA000926 | AURKB Antibody | Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-PA000927 | AURKB Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA070260 | Phospho-AURKB (Y12) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA070261 | Phospho-AURKB (T232) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-RA230110A0HU | AURKB Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IP |
AURKB Proteins
AURKB Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002458HU CSB-EP002458HU CSB-BP002458HU CSB-MP002458HU CSB-EP002458HU-B |
Recombinant Human Aurora kinase B (AURKB) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
