CADM1
CADM1(Cell Adhesion Molecule 1)也被稱為SynCAM1(Synaptic Cell Adhesion Molecule 1);參與多種生物學(xué)過程和疾病發(fā)生發(fā)展。 ADM1的胞外結(jié)構(gòu)域包括一個N-末端信號序列、三個Ig-like結(jié)構(gòu)域和一個C-末端結(jié)構(gòu)域,其中第一個Ig-like結(jié)構(gòu)域參與了細胞間的黏附和信號轉(zhuǎn)導(dǎo)。CADM1的細胞內(nèi)結(jié)構(gòu)域包括一個短的胞內(nèi)區(qū)域和一個長的胞內(nèi)區(qū)域,前者含有一個肽鍵酶切位點和幾個磷酸化位點,后者則包含多個蛋白質(zhì)相互作用位點和信號調(diào)節(jié)結(jié)構(gòu)域 它在神經(jīng)元、免疫細胞、腫瘤等細胞中表達,并通過其胞外結(jié)構(gòu)域和細胞內(nèi)信號通路影響細胞間的黏附、遷移、增殖和凋亡等生物學(xué)行為。
更多相關(guān)閱讀:CADM1/TSLC1:免疫球蛋白超家族黏附分子,一種新的TSG腫瘤抑制基因!
熱銷產(chǎn)品
Recombinant Mouse Cell adhesion molecule 1(Cadm1),partial (Active) CSB-MP004425MO
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse CADM1 at 2μg/mL can bind Mouse CRTAM (CSB-MP614820MO), the EC50?is 52.61-92.92 ng/mL.?
CADM1 Antibodies
CADM1 for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA004425GA01HU | CADM1 Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA004425ESR2HU | CADM1 Antibody | Human | ELISA, IHC |
CSB-PA112392 | CADM1 Antibody | Human,Mouse | ELISA,WB |
CSB-PA004340 | CADM1 Antibody | Human,Mouse | WB, IF, ELISA |
CADM1 Proteins
CADM1 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP004425MO CSB-EP004425MO CSB-BP004425MO CSB-EP004425MO-B |
Recombinant Mouse Cell adhesion molecule 1 (Cadm1), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
CSB-MP004425MO | Recombinant Mouse Cell adhesion molecule 1 (Cadm1), partial (Active) | Mammalian cell |
CADM1 Proteins for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP004425HU CSB-EP004425HU CSB-BP004425HU CSB-EP004425HU-B |
Recombinant Human Cell adhesion molecule 1 (CADM1), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |