Your Good Partner in Biology Research

CCL11

CCL11,即C-C motif chemokine ligand 11,也被稱作Eotaxin-1,是一種小型誘導性細胞因子,屬于C-C基序趨化因子家族成員之一。它在多種免疫細胞的遷移和活化中發(fā)揮關鍵作用,尤其是對嗜酸性粒細胞、嗜堿性粒細胞和Th2淋巴細胞具有強烈的化學吸引作用。CCL11通過與趨化因子受體如CCR2、CCR3和CCR5結合來發(fā)揮作用,其中CCR3是介導CCL11生物學效應的主要受體。CCL11參與了多種生理和病理過程,包括哮喘時嗜酸性粒細胞的歸巢、腫瘤微環(huán)境中免疫細胞的招募以及在衰老和神經(jīng)退行性疾病中的潛在作用。研究表明,CCL11在老年人中表達上調(diào),并與某些年齡相關疾病的發(fā)展相關聯(lián)。此外,CCL11的表達還與腫瘤微環(huán)境的免疫調(diào)節(jié)有關,可能影響腫瘤的發(fā)展和患者的預后。

熱銷產(chǎn)品

CCL11 Antibody (CSB-PA004775ESR2HU)

驗證數(shù)據(jù)

CSB-PA004775ESR2HU

Western blot
All lanes: CCL11 antibody at 5μg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 11 kDa
Observed band size: 11 kDa

CSB-PA004775ESR2HU

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA004775ESR2HU at dilution of 1:100

Rat Eotaxin 1 (Eotaxin 1/CCL11/ECF)ELISA Kit (CSB-E07319r)

驗證數(shù)據(jù)

CSB-E07319r 標準曲線

貨號:CSB-E07319r

規(guī)格:96T/48T

靈敏度:3.9 pg/ml

檢測范圍:15.6 pg/ml -1000 pg/ml

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CCL11 Antibodies

CCL11 for Homo sapiens (Human)

CCL11 Proteins

CCL11 Proteins for Cavia porcellus (Guinea pig)

CCL11 Proteins for Rattus norvegicus (Rat)

CCL11 Proteins for Mus musculus (Mouse)

CCL11 Proteins for Homo sapiens (Human)

CCL11 Proteins for Macaca mulatta (Rhesus macaque)

CCL11 Proteins for Equus caballus (Horse)

CCL11 Proteins for Bos taurus (Bovine)

CCL11 ELISA Kit

CCL11 ELISA Kit for Homo sapiens (Human)

CCL11 ELISA Kit for Rattus norvegicus (Rat)