CD58
CD58,即細(xì)胞表面分化抗原58,別名LFA-3、WLA等。它是一種由CD58基因編碼的糖蛋白,主要表達(dá)在多種白細(xì)胞表面,包括T細(xì)胞、B細(xì)胞、自然殺傷(NK)細(xì)胞等。CD58的作用機(jī)制涉及與T細(xì)胞表面的CD2受體結(jié)合,參與免疫細(xì)胞間的相互作用,調(diào)節(jié)免疫應(yīng)答。CD58與CD2的相互作用對(duì)于T細(xì)胞的激活至關(guān)重要,影響細(xì)胞毒性T細(xì)胞的殺傷活性和細(xì)胞因子的產(chǎn)生。此外,CD58還參與了免疫逃逸機(jī)制,某些病原體如單純皰疹病毒(HSV)通過(guò)表達(dá)與CD58相似的蛋白來(lái)逃避宿主的免疫監(jiān)視,是免疫學(xué)研究和相關(guān)疾病治療中的一個(gè)潛在靶點(diǎn)。
熱銷(xiāo)產(chǎn)品
CD58 Recombinant Monoclonal Antibody (CSB-RA166177A0HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Raji whole cell lysate, K562 whole cell lysate, Hela whole cell lysate
All lanes: CD58 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29, 27, 26 kDa
Observed band size: 55-70 kDa
CD58 Antibodies
CD58 for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
---|---|---|---|
CSB-PA004946GA01HU | CD58 Antibody | Human | ELISA,WB |
CSB-PA004946ESR1HU | CD58 Antibody | Human | ELISA, WB, IHC |
CSB-PA205850 | CD58 Antibody | Human | ELISA,WB |
CSB-PA001472 | CD58 Antibody | Human | WB, ELISA |
CSB-PA005227 | CD58 Antibody | Human | WB, ELISA |
CSB-RA166177A0HU | CD58 Recombinant Monoclonal Antibody | Human | ELISA, WB |
CD58 Proteins
CD58 Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
---|---|---|
CSB-YP004946HU1 CSB-EP004946HU1 CSB-BP004946HU1 CSB-MP004946HU1 CSB-EP004946HU1-B |
Recombinant Human Lymphocyte function-associated antigen 3 (CD58), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF004946HU | Recombinant Human Lymphocyte function-associated antigen 3 (CD58) | in vitro E.coli expression system |