CD69
CD69,也稱為“細(xì)胞粘附分子69”,是一種免疫細(xì)胞表面分子,屬于C型細(xì)胞粘附分子家族。其分子結(jié)構(gòu)包括細(xì)胞外區(qū)域、跨膜區(qū)域和胞內(nèi)區(qū)域。細(xì)胞外區(qū)域可以與其他細(xì)胞表面分子或細(xì)胞外基質(zhì)相互作用,從而參與細(xì)胞間的粘附和信號傳導(dǎo)。 CD69主要表達(dá)在激活的免疫細(xì)胞表面,如T淋巴細(xì)胞、B淋巴細(xì)胞、自然殺傷細(xì)胞(NK細(xì)胞)和某些組織的巨噬細(xì)胞等。在免疫細(xì)胞受到外界刺激(如抗原刺激)后,它會迅速表達(dá)在細(xì)胞表面,標(biāo)志著細(xì)胞的激活和應(yīng)答。在T細(xì)胞和B細(xì)胞的激活過程中,CD69的表達(dá)可以影響細(xì)胞的增殖、分化和細(xì)胞死亡。CD69表達(dá)在激活的免疫細(xì)胞表面,可能在細(xì)胞遷移過程中發(fā)揮作用。它可以影響細(xì)胞的黏附性和遷移能力,有助于免疫細(xì)胞在體內(nèi)尋找和定位感染或炎癥部位。CD69在炎癥和免疫應(yīng)答中也發(fā)揮重要作用。它參與調(diào)節(jié)炎癥反應(yīng)和免疫細(xì)胞的趨化和遷移。CD69的功能還與組織免疫調(diào)節(jié)和免疫耐受等生物學(xué)過程密切相關(guān)。 CD69的研究對于深入理解免疫細(xì)胞激活、遷移和調(diào)節(jié)的機(jī)制非常重要。它可能為免疫治療和疾病治療提供潛在的治療靶點。
更多相關(guān)閱讀:CD69:淋巴細(xì)胞活化最早表達(dá)的分子,作為多向性調(diào)控者參與血液和自身免疫疾??!
熱銷產(chǎn)品
● CD69 Recombinant Monoclonal Antibody CSB-RA004952MA1HU
驗證數(shù)據(jù)
The Binding Activity of Human CD69 with Anti-CD69 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD69 (CSB-MP004952HU) at 2 μg/mL can bind Anti-CD69 recombinant antibody , the EC50 is 23.17-26.04 ng/mL
● Recombinant Human Early activation antigen CD69(CD69),partial (Active) CSB-MP004952HU
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD69 at 2μg/mL can bind Anti-CD69 recombinant antibody (CSB-RA004952MA1HU), the EC50 is 23.17-26.04 ng/mL.
CD69 Antibodies
CD69 for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA004952GA01HU | CD69 Antibody | Human | ELISA,WB |
CSB-PA001473 | CD69 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA005841 | CD69 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-RA004952MA1HU | CD69 Recombinant Monoclonal Antibody | Human | ELISA |
CD69 Proteins
CD69 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP004952MO1 CSB-EP004952MO1 CSB-BP004952MO1 CSB-MP004952MO1 CSB-EP004952MO1-B |
Recombinant Mouse Early activation antigen CD69 (Cd69), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF004952MO | Recombinant Mouse Early activation antigen CD69 (Cd69) | in vitro E.coli expression system |
CD69 Proteins for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-MP004952HU | Recombinant Human Early activation antigen CD69 (CD69), partial (Active) | Mammalian cell |
CSB-EP004952HU-B | Recombinant Human Early activation antigen CD69 (Cd69), partial,Biotinylated | E.coli |