CD70
CD70是CD27配體。它在免疫系統(tǒng)中發(fā)揮重要作用,特別是在T細(xì)胞的活化和增殖過(guò)程中。他的結(jié)構(gòu)包括一個(gè)胞外區(qū)域、可以與CD27受體結(jié)合,一個(gè)跨膜區(qū)域和一個(gè)胞漿區(qū)域。CD70的主要功能之一是通過(guò)與CD27受體相互作用來(lái)調(diào)節(jié)T細(xì)胞的活化和增殖。CD27是T細(xì)胞表面的一種分子,當(dāng)CD70與其結(jié)合時(shí),會(huì)激活多條信號(hào)通路,包括NF-κB、MAPK和PI3K-Akt等信號(hào)通路。這些信號(hào)通路的激活可以促進(jìn)細(xì)胞增殖、分化和功能發(fā)揮,從而加強(qiáng)免疫應(yīng)答。此外,CD70還可以影響其他免疫細(xì)胞,如B細(xì)胞和自然殺傷細(xì)胞的功能。因此,對(duì)其結(jié)構(gòu)、功能和信號(hào)通路的深入理解對(duì)于免疫調(diào)節(jié)和相關(guān)疾病的治療具有重要意義。
熱銷(xiāo)產(chǎn)品
Recombinant Human CD70 antigen (CD70), partial (Active)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced/non-reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD70 at 2 μg/ml can bind Anti-CD70 antibody, the EC50 is 2.414-3.196 ng/mL
CD70 Antibodies
CD70 for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
---|---|---|---|
CSB-PA004954KA01HU | CD70 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA095181 | CD70 Antibody | Human | ELISA,WB |
CSB-PA001476 | CD70 Antibody | Human | WB, ELISA |
CSB-PA615999 | CD70 Antibody | Human | ELISA,IHC |
CSB-PA068483 | CD70 Antibody | Human | ELISA,IHC |
CSB-PA08009A0Rb | CD70 Antibody | Human | ELISA, IF |
CSB-PA08009B0Rb | CD70 Antibody, HRP conjugated | Human | ELISA |
CSB-PA08009C0Rb | CD70 Antibody, FITC conjugated | Human | |
CSB-RA004954MA1HU | CD70 Recombinant Monoclonal Antibody | Human | ELISA |
CD70 Proteins
CD70 Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
---|---|---|
CSB-YP004954HU | Recombinant Human CD70 antigen (CD70), partial | Yeast |
CSB-EP004954HU CSB-BP004954HU CSB-MP004954HU CSB-EP004954HU-B |
Recombinant Human CD70 antigen (CD70), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-MP004954HUc9 | Recombinant Human CD70 antigen (CD70), partial | Mammalian cell |
CSB-MP004954HU1 | Recombinant Human CD70 antigen (CD70), partial (Active) | Mammalian cell |
CD70 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
---|---|---|
CSB-YP004954MO1 CSB-EP004954MO1 CSB-BP004954MO1 CSB-MP004954MO1 CSB-EP004954MO1-B |
Recombinant Mouse CD70 antigen (Cd70), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF004954MO | Recombinant Mouse CD70 antigen (Cd70) | in vitro E.coli expression system |
CD70 Proteins for Sus scrofa (Pig)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
---|---|---|
CSB-YP670269PI CSB-EP670269PI CSB-BP670269PI CSB-MP670269PI CSB-EP670269PI-B |
Recombinant Pig CD70 antigen (CD70), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD70 ELISA Kit
CD70 ELISA Kit for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
---|---|---|---|
CSB-EL004954HU | Human CD70 antigen(CD70) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.039 ng/mL |
CD70 ELISA Kit for Mus musculus (Mouse)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
---|---|---|---|
CSB-EL004954MO | Mouse CD70 antigen(CD70) ELISA kit | Request Information |