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CNPY3

CNPY3,即C型鈉尿肽受體3,它是一種在多種組織中表達(dá)的蛋白質(zhì),尤其在心血管系統(tǒng)中的作用受到廣泛關(guān)注。CNPY3作為利鈉肽家族的共受體,參與調(diào)節(jié)體內(nèi)水電解質(zhì)平衡和血壓。其作用機(jī)制包括與C型鈉尿肽(CNP)結(jié)合,激活cGMP-PKG信號通路,導(dǎo)致血管舒張和尿鈉排泄增加。CNPY3通過與GC-A受體相互作用,參與信號傳導(dǎo),影響細(xì)胞內(nèi)cGMP水平,進(jìn)而調(diào)節(jié)心血管功能。在生物學(xué)意義上,CNPY3對維持心血管穩(wěn)態(tài)、促進(jìn)心肌保護(hù)和血管生成具有重要作用。CNPY3的功能異常與高血壓、心臟重塑和血管疾病等心血管疾病的發(fā)生發(fā)展密切相關(guān),是心血管疾病治療的潛在靶點。

熱銷產(chǎn)品

CNPY3 Antibody (CSB-PA874802ESR2HU)

驗證數(shù)據(jù)

CSB-PA874802ESR2HU

Western blot
All lanes: CNPY3 antibody at 1.2µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 31, 6 kDa
Observed band size: 31 kDa

CSB-PA874802ESR2HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA874802ESR2HU at dilution of 1:100

CSB-PA874802ESR2HU

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA874802ESR2HU at dilution of 1:100

CNPY3 Antibodies

CNPY3 for Homo sapiens (Human)

CNPY3 Proteins

CNPY3 Proteins for Homo sapiens (Human)