CTSK

CTSK，即組織蛋白酶K。別名Cathepsin K，它是一種由破骨細(xì)胞分泌的半胱氨酸蛋白酶，對(duì)骨吸收過(guò)程中的基質(zhì)膠原的降解至關(guān)重要。CTSK主要在破骨細(xì)胞中表達(dá)，但在其他類型的細(xì)胞中也有發(fā)現(xiàn)，如軟骨細(xì)胞和某些腫瘤細(xì)胞。CTSK在降解骨基質(zhì)中起關(guān)鍵作用，其活性受多種因素調(diào)節(jié)，包括pH值和特異性抑制劑。CTSK的作用機(jī)制涉及其對(duì)骨基質(zhì)中膠原蛋白的降解，這一過(guò)程對(duì)骨重塑和礦化至關(guān)重要。CTSK的異常表達(dá)或活性與多種疾病相關(guān)，包括但不限于骨疾病和腫瘤。在癌癥中，CTSK可能參與腫瘤的生長(zhǎng)和轉(zhuǎn)移，其表達(dá)水平的變化與腫瘤的侵襲性和預(yù)后相關(guān)。CTSK被認(rèn)為是治療骨質(zhì)疏松癥和某些癌癥的潛在靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Cathepsin K (CTSK) (CSB-EP006192HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CTSK Antibody (CSB-PA006192ESR1HU)

驗(yàn)證數(shù)據(jù)

Western blot
All lanes: CTSK antibody at 8μg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: Rat brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA006192ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA006192ESR1HU at dilution of 1:100

Human Cathepsin K,cath-K ELISA Kit (CSB-E09438h)

驗(yàn)證數(shù)據(jù)

貨號(hào)：CSB-E09438h

規(guī)格：96T/48T

靈敏度：1.95 pg/mL

檢測(cè)范圍：7.8 pg/mL-500 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CTSK Antibody

CTSK Protein

CTSK ELISA Kit

CTSK Antibodies

CTSK for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA006192LA01RA	Ctsk Antibody	Rat	ELISA, IHC

CTSK for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA006192GA01HU	CTSK Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA15119A0Rb	CTSK Antibody	Human	ELISA
CSB-PA006192ESR1HU	CTSK Antibody	Human, Rat	ELISA, WB, IHC
CSB-PA039740	CTSK Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA145433	CTSK Antibody	Human,Mouse,Rat	ELISA,IHC

CTSK Proteins

CTSK Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192HU	Recombinant Human Cathepsin K (CTSK)	Yeast
CSB-EP006192HU	Recombinant Human Cathepsin K (CTSK)	E.coli
CSB-BP006192HU CSB-MP006192HU CSB-EP006192HU-B	Recombinant Human Cathepsin K (CTSK)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSK Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192RB CSB-BP006192RB CSB-MP006192RB CSB-EP006192RB-B	Recombinant Rabbit Cathepsin K (CTSK)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192RB	Recombinant Rabbit Cathepsin K (Ctsk)	E.coli

CTSK Proteins for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192MO CSB-BP006192MO CSB-MP006192MO CSB-EP006192MO-B	Recombinant Mouse Cathepsin K (Ctsk)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192MO	Recombinant Mouse Cathepsin K (Ctsk)	E.coli

CTSK Proteins for Macaca mulatta (Rhesus macaque)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192MOW CSB-EP006192MOW CSB-BP006192MOW CSB-MP006192MOW CSB-EP006192MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Cathepsin K (CTSK)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSK Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192RA CSB-BP006192RA CSB-MP006192RA CSB-EP006192RA-B	Recombinant Rat Cathepsin K (Ctsk)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192RA	Recombinant Rat Cathepsin K (Ctsk)	E.coli

CTSK Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192MOV CSB-BP006192MOV CSB-MP006192MOV CSB-EP006192MOV-B	Recombinant Macaca fascicularis Cathepsin K (CTSK)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192MOV	Recombinant Macaca fascicularis Cathepsin K (CTSK)	E.coli

CTSK Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192CH CSB-EP006192CH CSB-BP006192CH CSB-MP006192CH CSB-EP006192CH-B	Recombinant Chicken Cathepsin K (CTSK)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSK Proteins for Sus scrofa (Pig)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192PI CSB-EP006192PI CSB-BP006192PI CSB-MP006192PI CSB-EP006192PI-B	Recombinant Pig Cathepsin K (CTSK)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSK Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192DO CSB-BP006192DO CSB-MP006192DO CSB-EP006192DO-B	Recombinant Dog Cathepsin K (CTSK)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSK Proteins for Bos taurus (Bovine)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP006192BO CSB-EP006192BO CSB-BP006192BO CSB-MP006192BO CSB-EP006192BO-B	Recombinant Bovine Cathepsin K (CTSK)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli