DAG1
Dystroglycan 1 (DAG1)是一種重要的跨膜蛋白,主要由α-和β-兩個(gè)亞基構(gòu)成,分別負(fù)責(zé)細(xì)胞外基質(zhì)配體的結(jié)合和與肌營(yíng)養(yǎng)不良蛋白復(fù)合物的連接。它在維持肌肉細(xì)胞穩(wěn)定性與完整性方面發(fā)揮關(guān)鍵作用,通過(guò)促進(jìn)肌細(xì)胞與基底膜的連接來(lái)確保正常功能。此外,DAG1還參與細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)過(guò)程,影響細(xì)胞的生長(zhǎng)、分化和遷移等生理活動(dòng)。DAG1的異常表達(dá)或功能失調(diào)與肌營(yíng)養(yǎng)不良癥、心肌病及某些癌癥等疾病緊密相關(guān),因此對(duì)其的深入研究有助于理解這些疾病的發(fā)病機(jī)制,并為疾病治療提供新的思路
熱銷(xiāo)產(chǎn)品
Recombinant Human Dystroglycan (DAG1), partial
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
DAG1 Antibodies
DAG1 for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
---|---|---|---|
CSB-PA006488GA01HU | DAG1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA613486NA01HU | DAG1 Antibody | Human | ELISA, IHC |
CSB-PA613486NB01HU | DAG1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA613486ND01HU | DAG1 Antibody, Biotin conjugated | Human | ELISA |
DAG1 Proteins
DAG1 Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
---|---|---|
CSB-MP613486HU CSB-EP613486HU-B |
Recombinant Human Dystroglycan (DAG1), partial | Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP613486HU | Recombinant Human Dystroglycan (DAG1), partial | E.coli |
CSB-YP613486HU | Recombinant Human Dystroglycan (DAG1), partial | Yeast |
CSB-BP613486HU | Recombinant Human Dystroglycan (DAG1), partial | Baculovirus |
DAG1 ELISA Kit
DAG1 ELISA Kit for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
---|---|---|---|
CSB-EL006488HU | Human dystroglycan 1 (dystrophin-associated glycoprotein 1) (DAG1) ELISA kit | serum, plasma, tissue homogenates | 31.25 pg/mL |