EGLN1
EGLN1，九同源物1，又稱C1orf12、DKFZp761F179、ECYT3、HIFPH2、HPH2、PHD2、SM-20、SM20、ZMYND6等。它來源于多個物種，包括人類，并主要通過原核表達(dá)系統(tǒng)如E.coli生產(chǎn)。EGLN1作為機體最主要的氧氣感受器，在有氧條件下，利用氧氣作為輔因子羥基化修飾低氧誘導(dǎo)因子HIF-α，進(jìn)而促進(jìn)其降解；而在低氧條件下，EGLN1活性受抑制，HIF-α積累并調(diào)控低氧下游基因表達(dá)，對細(xì)胞代謝和增殖等生物學(xué)過程具有重要意義。此外，EGLN1還參與抗病毒先天免疫等生物學(xué)過程。
熱銷產(chǎn)品
Recombinant Human Egl nine homolog 1 (EGLN1), partial (CSB-EP863932HU1b1)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
EGLN1 Antibody (CSB-PA863932ESR2HU)
驗證數(shù)據(jù)
Western blot
All lanes: Egl nine homolog 1 antibody at 12μg/ml + Rat brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 47, 44, 37 kDa
Observed band size: 47 kDa
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA863932ESR2HU at dilution of 1:100
EGLN1 Antibodies
EGLN1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007481GA01HU | EGLN1 Antibody | Human | ELISA,WB,IHC,IF |
| CSB-PA863932ESR1HU | EGLN1 Antibody | Human | ELISA, IHC |
| CSB-PA863932ESR2HU | EGLN1 Antibody | Human, Rat | ELISA, WB, IHC |
| CSB-PA519093 | EGLN1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA958222 | EGLN1 Antibody | Human,Mouse,Rat | ELISA,IHC |
EGLN1 Proteins
EGLN1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007481RA CSB-EP007481RA CSB-BP007481RA CSB-MP007481RA CSB-EP007481RA-B |
Recombinant Rat Egl nine homolog 1 (Egln1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EGLN1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP821019MO CSB-EP821019MO CSB-BP821019MO CSB-MP821019MO CSB-EP821019MO-B |
Recombinant Mouse Egl nine homolog 1 (Egln1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EGLN1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP863932HU CSB-EP863932HU CSB-BP863932HU CSB-MP863932HU CSB-EP863932HU-B |
Recombinant Human Egl nine homolog 1 (EGLN1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP863932HU1b1 | Recombinant Human Egl nine homolog 1 (EGLN1), partial | E.coli |
| CSB-EP863932HU1 | Recombinant Human Egl nine homolog 1 (EGLN1), partial | E.coli |
