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F9

F9,即凝血因子IX,它是一種維生素K依賴(lài)的凝血蛋白,由F9基因編碼,在肝臟中合成。F9在血液中以非活性酶原形式循環(huán),通過(guò)因子X(jué)Ia的激活去除激活肽后,生成由二硫鍵連接的重鏈和輕鏈的活性形式。F9的作用機(jī)制是在凝血級(jí)聯(lián)中與Ca+2離子、膜磷脂和因子VIII相互作用,將因子X(jué)激活到其活性形式,從而參與血液凝固過(guò)程。F9對(duì)于正常的血液凝固至關(guān)重要,F(xiàn)9基因的變異可導(dǎo)致因子IX缺乏,引起一種隱性X連鎖疾病,即血友病B或圣誕病。

熱銷(xiāo)產(chǎn)品

F9 Recombinant Monoclonal Antibody (CSB-RA923075A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA923075A0HU

Western Blot
Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate, K562 whole cell lysate
All lanes: Factor IX antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 52 kDa
Observed band size: 52 kDa

F9 Antibodies

F9 for Homo sapiens (Human)

F9 Proteins

F9 Proteins for Sus scrofa (Pig)

F9 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

F9 Proteins for Cavia porcellus (Guinea pig)

F9 Proteins for Ovis aries (Sheep)

F9 Proteins for Oryctolagus cuniculus (Rabbit)

F9 Proteins for Mus musculus (Mouse)

F9 Proteins for Homo sapiens (Human)

F9 Proteins for Bos taurus (Bovine)

F9 Proteins for Rattus norvegicus (Rat)

F9 Proteins for Vaccinia virus (strain L-IVP) (VACV)

F9 Proteins for Felis catus (Cat) (Felis silvestris catus)

F9 Proteins for Pan troglodytes (Chimpanzee)

F9 ELISA Kit

F9 ELISA Kit for Homo sapiens (Human)