FANCA
FANCA基因編碼的蛋白質(zhì)是范科尼貧血互補(bǔ)組（FANC）的關(guān)鍵成員，其結(jié)構(gòu)可能涉及多個(gè)亞型的轉(zhuǎn)錄變體。雖然FANCA直接參與的特定信號(hào)通路尚不完全明確，但它在DNA損傷修復(fù)和維持基因組穩(wěn)定性方面發(fā)揮著至關(guān)重要的作用。FANCA與其他FANC蛋白共同作用，被招募到DNA損傷位點(diǎn)，參與DNA修復(fù)過(guò)程，從而防止細(xì)胞突變、癌癥和遺傳性疾病的發(fā)生。FANCA的功能異?；蛲蛔儠?huì)導(dǎo)致范科尼貧血，這是一種遺傳性骨髓衰竭綜合征。因此，對(duì)FANCA基因及其編碼的蛋白質(zhì)的研究對(duì)于理解和治療范科尼貧血等疾病具有重要意義。
熱銷產(chǎn)品
FANCA Antibody (CSB-PA008413LA01HU)
驗(yàn)證數(shù)據(jù)
Immunofluorescent analysis of Hela cells using CSB-PA008413LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
FANCA Antibodies
FANCA for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA008413GA01HU | FANCA Antibody | Human | ELISA,WB,IHC |
| CSB-PA008175 | Phospho-FANCA (S1149) Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA008176 | FANCA Antibody | Human | IHC, ELISA |
| CSB-PA008413LA01HU | FANCA Antibody | Human | ELISA, IF |
| CSB-PA008413LB01HU | FANCA Antibody, HRP conjugated | Human | ELISA |
| CSB-PA008413LC01HU | FANCA Antibody, FITC conjugated | Human | |
| CSB-PA008413LD01HU | FANCA Antibody, Biotin conjugated | Human | ELISA |
FANCA Proteins
FANCA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP008413HU CSB-EP008413HU CSB-BP008413HU CSB-MP008413HU CSB-EP008413HU-B |
Recombinant Human Fanconi anemia group A protein (FANCA), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
