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HTR3A

HTR3A,即5-羥色胺受體3A,別名5-HT3A受體。它是一種由HTR3A基因編碼的配體門控離子通道型受體,主要在中樞和外周神經(jīng)系統(tǒng)中表達(dá)。HTR3A的作用機(jī)制涉及與5-羥色胺(5-HT)結(jié)合,引起通道開(kāi)啟,允許陽(yáng)離子流動(dòng),進(jìn)而影響神經(jīng)元的興奮性。HTR3A在調(diào)節(jié)疼痛感知、惡心、嘔吐以及情緒等方面發(fā)揮作用。HTR3A參與了多種生理和病理過(guò)程的調(diào)控,包括胃腸道運(yùn)動(dòng)、心血管功能、呼吸節(jié)律等。HTR3A的異常表達(dá)或功能失調(diào)與某些疾病有關(guān),如焦慮癥、抑郁癥、精神分裂癥、腸易激綜合癥等。HTR3A是精神藥理學(xué)研究和相關(guān)疾病治療中的一個(gè)潛在靶點(diǎn)。

熱銷產(chǎn)品

HTR3A Antibody (CSB-PA010890LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA010890LA01HU

Western Blot
Positive WB detected in: Rat lung tissue, Mouse lung tissue
All lanes: HTR3A antibody at 2.5μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 56, 59, 54, 60 kDa
Observed band size: 56 kDa

CSB-PA010890LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA010890LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

HTR3A Antibodies

HTR3A for Homo sapiens (Human)

HTR3A Proteins

HTR3A Proteins for Homo sapiens (Human)