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IGFBP2

IGFBP2,即胰島素樣生長因子結(jié)合蛋白2,別名IGFBP-2、IBP-2等。它是由IGFBP2基因編碼的蛋白質(zhì),在多種細胞和組織中廣泛表達。IGFBP2的主要作用機制是通過與胰島素樣生長因子(IGF)結(jié)合,調(diào)節(jié)IGF的生物可用性,影響細胞的生長、分化和凋亡。此外,IGFBP2還能通過影響細胞周期和抑制細胞增殖來發(fā)揮其生物學(xué)功能。它參與了細胞增殖、細胞遷移、組織修復(fù)和腫瘤發(fā)展等過程。IGFBP2的異常表達與多種疾病相關(guān),尤其是在腫瘤生物學(xué)中,IGFBP2的高表達與腫瘤的侵襲性和預(yù)后不良有關(guān)。因此,IGFBP2是腫瘤治療研究中的一個潛在靶點。

熱銷產(chǎn)品

IGFBP2 Recombinant Monoclonal Antibody (CSB-RA225697A0HU)

驗證數(shù)據(jù)

CSB-RA225697A0HU

Western Blot
Positive WB detected in: MCF-7 whole cell lysate
All lanes: IGFBP2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 35 kDa
Observed band size: 35 kDa

CSB-RA225697A0HU

IHC image of CSB-RA225697A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

IGFBP2 Antibodies

IGFBP2 for Homo sapiens (Human)

IGFBP2 Proteins

IGFBP2 Proteins for Homo sapiens (Human)

IGFBP2 ELISA Kit

IGFBP2 ELISA Kit for Homo sapiens (Human)