IL34
IL-34是一種新型的白細(xì)胞介素,由241個(gè)氨基酸組成的同源二聚體蛋白,位于人類16號(hào)染色體上。它通過(guò)與集落刺激因子1受體(CSF-1R)結(jié)合,激活包括PI3K/AKT在內(nèi)的細(xì)胞內(nèi)信號(hào)通路,進(jìn)而調(diào)節(jié)細(xì)胞的增殖、存活、分化及炎癥反應(yīng)等生物學(xué)過(guò)程。IL-34在免疫系統(tǒng)中扮演重要角色,促進(jìn)單核細(xì)胞和巨噬細(xì)胞的增殖、存活和分化,對(duì)先天免疫和炎癥反應(yīng)具有顯著的調(diào)節(jié)作用。此外,IL-34與多種疾病的發(fā)生和發(fā)展密切相關(guān),如類風(fēng)濕關(guān)節(jié)炎、心血管疾病和自身免疫疾病等。因此,深入研究IL-34的信號(hào)通路和作用機(jī)制對(duì)于理解其生物學(xué)功能及在疾病中的作用具有重要意義。
熱銷產(chǎn)品
Human Interleukin-34(IL34) ELISA kit (CSB-EL011657HU)
驗(yàn)證數(shù)據(jù)
貨號(hào):CSB-EL011657HU
規(guī)格:96T/48T
靈敏度:5.86 pg/mL
檢測(cè)范圍:23.5 pg/mL-1500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
IL34 Antibodies
IL34 for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA751146LA01HU | IL34 Antibody | Human | ELISA, WB, IHC |
CSB-PA751146LB01HU | IL34 Antibody, HRP conjugated | Human | ELISA |
CSB-PA751146LC01HU | IL34 Antibody, FITC conjugated | Human | |
CSB-PA751146LD01HU | IL34 Antibody, Biotin conjugated | Human | ELISA |
IL34 Proteins
IL34 Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
---|---|---|
CSB-YP751146HU CSB-EP751146HU CSB-BP751146HU CSB-MP751146HU CSB-EP751146HU-B |
Recombinant Human Interleukin-34 (IL34) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL34 ELISA Kit
IL34 ELISA Kit for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
---|---|---|---|
CSB-EL011657HU | Human Interleukin-34(IL34) ELISA kit | serum, plasma, tissue homogenates, cell culture supernates | 5.86 pg/mL |