LMP1
LMP1，即大分子多肽1，別名LMP-1、CD340。它是一種由EB病毒（Epstein-Barr virus, EBV）編碼的膜蛋白，屬于腫瘤壞死因子受體超家族成員。LMP1在EBV感染的B淋巴細(xì)胞中表達(dá)，其作用機(jī)制涉及激活多條信號通路，包括NF-κB、JAK/STAT、PI3K/AKT等，從而促進(jìn)細(xì)胞的存活、增殖和抗凋亡。LMP1對EBV相關(guān)腫瘤的促進(jìn)作用，如霍奇金淋巴瘤、鼻咽癌等。LMP1的表達(dá)有助于病毒逃避宿主的免疫監(jiān)視，促進(jìn)病毒的持續(xù)感染和腫瘤細(xì)胞的存活，是EBV相關(guān)腫瘤研究和治療的重要靶點。
熱銷產(chǎn)品
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數(shù)據(jù)
Western blot analysis of extracts from K562, Jurkat, HepG2, HuvEc, HeLa and COLO205 cells, using LAMP1 antibody.
LMP1 Antibodies
LMP1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA616273 | LAMP1 Antibody | Human | ELISA,WB |
| CSB-PA005240 | LAMP1 Antibody | Human,Rat | WB, ELISA |
| CSB-PA009777 | LAMP1 Antibody | Human | WB, ELISA |
LMP1 Proteins
LMP1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012738HU1 CSB-EP012738HU1 CSB-BP012738HU1 CSB-MP012738HU1 CSB-EP012738HU1-B |
Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012738HU | Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1) | in vitro E.coli expression system |
| CSB-AP005091HU | Recombinant Human Lysosome-associated membrane glycoprotein 1 (LAMP1), partial (Active) | Mammalian cell |
