LONP1
LONP1,即線粒體ATP依賴性蛋白酶,別名PIM1、Protease serine 15、PRSS15、Serine protease 15。它是一種由LONP1基因編碼的線粒體蛋白酶,具有蛋白水解、分子伴侶和mtDNA結(jié)合等多重功能。LONP1通過降解錯(cuò)誤折疊或損壞的蛋白質(zhì)來維持線粒體蛋白質(zhì)的穩(wěn)態(tài),參與調(diào)節(jié)氧化應(yīng)激反應(yīng)、熱休克反應(yīng)以及線粒體DNA的穩(wěn)定性。LONP1在心臟保護(hù)、腫瘤進(jìn)展、代謝調(diào)控等生物學(xué)過程中發(fā)揮重要作用,其活性的變化與多種疾病的發(fā)生發(fā)展密切相關(guān),是細(xì)胞生理和病理研究中的關(guān)鍵分子。
熱銷產(chǎn)品
Recombinant Human Lon protease homolog, mitochondrial (LONP1), partial (CSB-EP013032HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
LONP1 Antibodies
LONP1 for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA013032GA01HU | LONP1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA897125 | LONP1 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA958239 | LONP1 Antibody | Human,Mouse | ELISA,WB,IHC |
CSB-PA013032LA01HU | LONP1 Antibody | Human | ELISA, IHC, IF |
CSB-PA013032LB01HU | LONP1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA013032LC01HU | LONP1 Antibody, FITC conjugated | Human | |
CSB-PA013032LD01HU | LONP1 Antibody, Biotin conjugated | Human | ELISA |
LONP1 Proteins
LONP1 Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP013032HU CSB-BP013032HU CSB-MP013032HU CSB-EP013032HU-B |
Recombinant Human Lon protease homolog, mitochondrial (LONP1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP013032HU | Recombinant Human Lon protease homolog, mitochondrial (LONP1), partial | E.coli |