METTL14
METTL14，即甲基轉(zhuǎn)移酶樣蛋白14，別名KIAA1539。它是一種由METTL14基因編碼的蛋白質(zhì)，具有甲基化轉(zhuǎn)移酶活性，參與RNA的m6A甲基化修飾。METTL14的作用機(jī)制是通過其甲基化活性，特異性地在RNA分子的腺苷酸上添加甲基，形成N6-甲基腺苷酸(m6A)，這種修飾在調(diào)控mRNA的穩(wěn)定性、剪接、轉(zhuǎn)運(yùn)和翻譯中發(fā)揮作用。METTL14的功能異常與多種疾病有關(guān)，尤其是在癌癥中，METTL14的異常表達(dá)或活性改變可能導(dǎo)致腫瘤細(xì)胞的增殖和轉(zhuǎn)移。此外，METTL14在神經(jīng)系統(tǒng)發(fā)育和認(rèn)知功能中也發(fā)揮作用，其突變與某些神經(jīng)發(fā)育障礙相關(guān)。
熱銷產(chǎn)品
Recombinant Human N6-adenosine-methyltransferase non-catalytic subunit (METTL14) (CSB-EP884519HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
METTL14 Antibody (CSB-PA884519LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: SH-SY5Y whole cell lysate
All lanes: METTL14 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 53 kDa
Observed band size: 53 kDa
METTL14 Antibodies
METTL14 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA884519LA01HU | METTL14 Antibody | Human | ELISA, WB |
| CSB-PA884519LB01HU | METTL14 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA884519LC01HU | METTL14 Antibody, FITC conjugated | Human | |
| CSB-PA884519LD01HU | METTL14 Antibody, Biotin conjugated | Human | ELISA |
METTL14 Proteins
METTL14 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013729BO CSB-EP013729BO CSB-BP013729BO CSB-MP013729BO CSB-EP013729BO-B |
Recombinant Bovine N6-adenosine-methyltransferase non-catalytic subunit (METTL14) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
METTL14 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP667575MO CSB-EP667575MO CSB-BP667575MO CSB-MP667575MO CSB-EP667575MO-B |
Recombinant Mouse Methyltransferase-like protein 14 (Mettl14) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
METTL14 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP724142XBF CSB-EP724142XBF CSB-BP724142XBF CSB-MP724142XBF CSB-EP724142XBF-B |
Recombinant Xenopus tropicalis Methyltransferase-like protein 14 (mettl14) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
METTL14 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP726511CH CSB-EP726511CH CSB-BP726511CH CSB-MP726511CH CSB-EP726511CH-B |
Recombinant Chicken Methyltransferase-like protein 14 (METTL14) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
METTL14 Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP732620PYX CSB-EP732620PYX CSB-BP732620PYX CSB-MP732620PYX CSB-EP732620PYX-B |
Recombinant Pongo abelii Methyltransferase-like protein 14 (METTL14) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
METTL14 Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP747347XBE CSB-EP747347XBE CSB-BP747347XBE CSB-MP747347XBE CSB-EP747347XBE-B |
Recombinant Xenopus laevis Methyltransferase-like protein 14 (mettl14) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
METTL14 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP757538DIL CSB-EP757538DIL CSB-BP757538DIL CSB-MP757538DIL CSB-EP757538DIL-B |
Recombinant Danio rerio Methyltransferase-like protein 14 (mettl14) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
METTL14 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP884519HU CSB-BP884519HU CSB-MP884519HU CSB-EP884519HU-B |
Recombinant Human N6-adenosine-methyltransferase non-catalytic subunit (METTL14) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP884519HU | Recombinant Human N6-adenosine-methyltransferase non-catalytic subunit (METTL14) | E.coli |
