PPARA

PPARA，即過氧化物酶體增殖物激活受體α，別名包括PPARα、NR1C1。PPARA是一種核受體，屬于PPAR家族成員之一，由人體細(xì)胞自身的基因編碼。PPARA在肝臟、心臟、骨骼肌、腎臟和棕色脂肪組織等多種組織中表達(dá)。其作用機(jī)制主要是通過與特定的配體結(jié)合，如脂肪酸和其衍生物，激活受體，形成異源二聚體與DNA上的PPAR響應(yīng)元件（PPREs）結(jié)合，調(diào)控下游基因的表達(dá)，從而參與脂質(zhì)代謝、能量平衡和細(xì)胞增殖等過程。PPARA在生物學(xué)上的意義非常廣泛，它在調(diào)節(jié)脂肪酸氧化、膽固醇代謝、炎癥反應(yīng)、細(xì)胞分化和腫瘤發(fā)生等方面發(fā)揮關(guān)鍵作用。PPARA的激活可以促進(jìn)線粒體脂肪酸氧化，提高能量代謝效率，降低血漿中的膽固醇和甘油三酯水平，對(duì)抗動(dòng)脈粥樣硬化。此外，PPARA還參與調(diào)節(jié)肝臟的解毒功能，影響藥物和毒物的代謝。PPARA的激動(dòng)劑，如纖維酸類藥物，被廣泛用于治療高脂血癥和相關(guān)心血管疾病。因此，PPARA是代謝性疾病和心血管疾病研究和治療中的一個(gè)重要靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Peroxisome proliferator-activated receptor alpha (PPARA) (CSB-BP018421HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of Baculovirus host and target protein, the LC-MS/MS Analysis result of CSB-BP018421HU could indicate that this peptide derived from Baculovirus-expressed Homo sapiens (Human) PPARA.

PPARA Antibody (CSB-PA030137)

驗(yàn)證數(shù)據(jù)

Western Blot analysis of 3T3 cells using PPAR-α Polyclonal Antibody

Human peroxisome proliferators activator receptors alpha,PPAR-α ELISA Kit (CSB-E09754h)

驗(yàn)證數(shù)據(jù)

貨號(hào)：CSB-E09754h

規(guī)格：96T/48T

靈敏度：19.5 pg/mL

檢測范圍：78 pg/mL-5000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PPARA Antibody

PPARA Protein

PPARA ELISA Kit

PPARA Antibodies

PPARA for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA018421GA01HU	PPARA Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA030137	PPARA Antibody	Human,Mouse,Rat	WB, IF, ELISA
CSB-PA945095	PPARA Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA112569	PPARA Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA018421LA01HU	PPARA Antibody	Human	ELISA, WB
CSB-PA018421LB01HU	PPARA Antibody,HRP conjugated	Human	ELISA
CSB-PA018421LC01HU	PPARA Antibody，F(xiàn)ITC conjugated	Human
CSB-PA018421LD01HU	PPARA Antibody，Biotin conjugated	Human	ELISA

PPARA Proteins

PPARA Proteins for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP018421MO CSB-EP018421MO CSB-BP018421MO CSB-MP018421MO CSB-EP018421MO-B	Recombinant Mouse Peroxisome proliferator-activated receptor alpha (Ppara)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPARA Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP018421RA CSB-EP018421RA CSB-BP018421RA CSB-MP018421RA CSB-EP018421RA-B	Recombinant Rat Peroxisome proliferator-activated receptor alpha (Ppara)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPARA Proteins for Cavia porcellus (Guinea pig)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP018421GU CSB-EP018421GU CSB-BP018421GU CSB-MP018421GU CSB-EP018421GU-B	Recombinant Guinea pig Peroxisome proliferator-activated receptor alpha (PPARA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPARA Proteins for Xenopus laevis (African clawed frog)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP018421XBE CSB-EP018421XBE CSB-BP018421XBE CSB-MP018421XBE CSB-EP018421XBE-B	Recombinant Xenopus laevis Peroxisome proliferator-activated receptor alpha (ppara)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPARA Proteins for Phascolarctos cinereus (Koala)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP018421EUM CSB-EP018421EUM CSB-BP018421EUM CSB-MP018421EUM CSB-EP018421EUM-B	Recombinant Phascolarctos cinereus Peroxisome proliferator-activated receptor alpha (PPARA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PPARA Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來源
CSB-YP018421DO CSB-EP018421DO CSB-BP018421DO CSB-MP018421DO CSB-EP018421DO-B	Recombinant Dog Peroxisome proliferator-activated receptor alpha (PPARA)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli