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PROM1

PROM1(Prominin-1),又稱為CD133,是一種廣泛表達(dá)于多種細(xì)胞類型中的跨膜糖蛋白。包括造血干細(xì)胞、神經(jīng)干細(xì)胞以及多種組織中的上皮細(xì)胞等。在癌癥中,PROM1已被鑒定為癌干細(xì)胞標(biāo)志物,與腫瘤的起始、發(fā)展和化療抵抗等相關(guān)聯(lián)。多項(xiàng)研究表明,針對(duì)PROM1表達(dá)或功能的調(diào)控可以成為治療癌癥的潛在策略。因此,PROM1是一個(gè)潛在的治療靶點(diǎn),可能會(huì)為癌癥治療提供新的方向。通過(guò)進(jìn)一步研究PROM1的生物學(xué)功能和分子機(jī)制,可能有助于揭示其在癌癥發(fā)展中的作用,并為開發(fā)新的癌癥治療藥物提供理論基礎(chǔ)。

更多PROM1相關(guān)內(nèi)容:一種新的腫瘤干細(xì)胞CSCs表面標(biāo)志物,未來(lái)新分子靶點(diǎn)!

熱銷產(chǎn)品

Recombinant Human Prominin-1(PROM1)-VLPs (Active) CSB-MP018751HU(A4)

驗(yàn)證數(shù)據(jù)

SDS
CSB-MP018751HU(A4) SDS

CSB-MP018751HU(A4) is detected by Mouse anti-6*His monoclonal antibody.

ELISA
CSB-MP018751HU(A4) ELISA

Activity
Measured by its binding ability in a functional ELISA. Immobilized PROM1 at 5 μg/mL can bind Anti-PROM1 recombinant antibody (CSB-RA018751MA1HU), the EC50 is 0.4322-0.7189 ng/mL.

PROM1 Recombinant Monoclonal Antibody CSB-RA018751MA1HU

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ELISA
CSB-RA018751MA1HU ELISA

The Binding Activity of PROM1 with Anti-PROM1 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized PROM1 (CSB-MP018751HU(A4)) at 5 μg/mL can bind Anti-PROM1 recombinant antibody, the EC50 is 0.4322-0.7189 ng/mL.

PROM1 Antibodies

PROM1 for Homo sapiens (Human)

PROM1 Proteins

PROM1 Proteins for Homo sapiens (Human)

PROM1 Proteins for Mus musculus (Mouse)