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SERPINA5

SERPINA5,即絲氨酸蛋白酶抑制劑家族A成員5,是一種在人體血液中表達(dá)的蛋白質(zhì),由SERPINA5基因編碼。它是一種依賴肝素的絲氨酸蛋白酶抑制劑,主要在體液和分泌液中發(fā)揮作用。SERPINA5通過不可逆地結(jié)合到絲氨酸蛋白酶的活性位點(diǎn),從而抑制這些酶的活性。它在血管內(nèi)外的蛋白水解活動調(diào)節(jié)中扮演重要角色,參與血液凝固和炎癥反應(yīng),通過抑制抗凝因子活化蛋白C以及凝血因子,如凝血酶原、因子XI、因子Xa、血漿激肽釋放酶等,發(fā)揮止血和促進(jìn)凝血的作用。在生物學(xué)意義上,SERPINA5的表達(dá)異常與多種疾病相關(guān),包括血栓形成、癲癇、遺傳性球形紅細(xì)胞增多癥等,是血液系統(tǒng)和炎癥性疾病研究中的一個重要分子。

熱銷產(chǎn)品

Recombinant Mouse Plasma serine protease inhibitor (Serpina5) (CSB-BP021061MO)

驗證數(shù)據(jù)

CSB-BP021061MO

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

SERPINA5 Antibody (CSB-PA021061LA01HU)

驗證數(shù)據(jù)

CSB-PA021061LA01HU

Western Blot
Positive WB detected in: Rat liver tissue, Mouse liver tissue
All lanes: SERPINA5 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 46 kDa
Observed band size: 46 kDa

CSB-PA021061LA01HU

Immunohistochemistry analysis of human ovarian cancer using CSB-PA021061LA01HU at dilution of 1:100

CSB-PA021061LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA021061LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

SERPINA5 Antibodies

SERPINA5 for Homo sapiens (Human)

SERPINA5 Proteins

SERPINA5 Proteins for Mus musculus (Mouse)

SERPINA5 Proteins for Homo sapiens (Human)

SERPINA5 Proteins for Bos taurus (Bovine)

SERPINA5 ELISA Kit

SERPINA5 ELISA Kit for Homo sapiens (Human)