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SLC39A6

SLC39A6 (Solute Carrier Family 39 Member 6)是一種轉(zhuǎn)運(yùn)蛋白,負(fù)責(zé)將錳、鐵和鋅等離子從細(xì)胞外膜運(yùn)輸?shù)郊?xì)胞內(nèi)。它在人體中廣泛表達(dá),尤其在腦組織中表達(dá)水平較高。SLC39A6參與許多生理和病理過(guò)程,包括神經(jīng)發(fā)育、免疫調(diào)節(jié)、細(xì)胞凋亡和代謝調(diào)節(jié)等。 近年來(lái)的研究發(fā)現(xiàn),SLC39A6在某些癌癥中的表達(dá)水平異常,如乳腺癌、結(jié)腸癌、胃癌和前列腺癌等。SLC39A6的過(guò)度表達(dá)被認(rèn)為與某些癌癥的發(fā)生和發(fā)展有關(guān),如通過(guò)促進(jìn)癌細(xì)胞增殖和轉(zhuǎn)移。因此,SLC39A6成為了一個(gè)重要的癌癥靶點(diǎn),可以通過(guò)調(diào)節(jié)SLC39A6的表達(dá)和活性,以開(kāi)發(fā)新的治療癌癥的策略。此外,SLC39A6也被認(rèn)為是神經(jīng)退行性疾病的潛在治療靶點(diǎn)。

更多SLC39A6相關(guān)閱讀:鋅離子轉(zhuǎn)運(yùn)蛋白,抗體偶聯(lián)藥物ADC新晉靶點(diǎn)!

熱銷產(chǎn)品

Recombinant Human SLC39A6, partial (Active) (CSB-BP621669HU1)

驗(yàn)證數(shù)據(jù)

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC39A6 at 1 μg/ml can bind Anti-SLC39A6 recombinant antibody (CSB-RA621669MA1HU), the EC50 is 0.6873-0.9010 ng/mL.

SLC39A6 Recombinant Monoclonal Antibody CSB-RA621669MA1HU

驗(yàn)證數(shù)據(jù)

ELISA
High Purity Validated of CSB-RA621669MA1HU

The Binding Activity of SLC39A6 with anti-SLC39A6 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC39A6(CSB-BP621669HU) at 1 μg/ml can bind Anti-SLC39A6-1 recombinant antibody, the EC50 is 0.6873-0.9010 ng/mL.

SLC39A6 Antibodies

SLC39A6 for Homo sapiens (Human)

SLC39A6 Proteins

SLC39A6 Proteins for Homo sapiens (Human)

SLC39A6 Proteins for Rattus norvegicus (Rat)

SLC39A6 Proteins for Pongo abelii (Sumatran orangutan)

SLC39A6 Proteins for Mus musculus (Mouse)