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SLITRK6

SLITRK6,即SLIT和NTRK樣家族成員6,別名DFNMYP等。它是一種在神經(jīng)組織中主要表達(dá)的膜蛋白,具有兩個(gè)N末端富含亮氨酸的重復(fù)序列(LRR)結(jié)構(gòu)域和一個(gè)與神經(jīng)營(yíng)養(yǎng)因子受體Trk具有同源性的C末端區(qū)域。SLITRK6在神經(jīng)突生長(zhǎng)的調(diào)節(jié)中起著關(guān)鍵作用,對(duì)維持正常聽力和視力至關(guān)重要。其作用機(jī)制可能涉及與SLITRK家族其他成員相似的神經(jīng)突導(dǎo)向和細(xì)胞間通訊的調(diào)節(jié)。SLITRK6的突變與近視和耳聾等疾病有關(guān),且在某些腦腫瘤中表達(dá)水平較高,提示其在神經(jīng)系統(tǒng)疾病中的潛在作用。

熱銷產(chǎn)品

SLITRK6 Antibody (CSB-PA867155LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA867155LA01HU

Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA867155LA01HU at dilution of 1:100

CSB-PA867155LA01HU

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA867155LA01HU at dilution of 1:100

CSB-PA867155LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA867155LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

SLITRK6 Antibodies

SLITRK6 for Homo sapiens (Human)

SLITRK6 Proteins

SLITRK6 Proteins for Mus musculus (Mouse)

SLITRK6 Proteins for Homo sapiens (Human)