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SPG21

Maspardin is a protein in humans that is encoded by SPG21 gene. Maspardin is a protein that in humans is encoded by the SPG21 gene. The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4.

SPG21 Antibodies

SPG21 for Homo sapiens (Human)

SPG21 Proteins

SPG21 Proteins for Xenopus laevis (African clawed frog)

SPG21 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

SPG21 Proteins for Rattus norvegicus (Rat)

SPG21 Proteins for Pongo abelii (Sumatran orangutan)

SPG21 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

SPG21 Proteins for Bos taurus (Bovine)

SPG21 Proteins for Mus musculus (Mouse)

SPG21 Proteins for Homo sapiens (Human)