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TBC1D4

TBC1D4,即TBC1域家族成員4,別名TBC1D4、RAB7L1等。它是一種由TBC1D4基因編碼的蛋白激酶,屬于TBC1域蛋白家族成員之一,在多種組織中表達(dá)。TBC1D4的作用機(jī)制涉及G蛋白信號(hào)傳導(dǎo)的調(diào)控,特別是通過其TBC結(jié)構(gòu)域?qū)ab GTP酶的活性進(jìn)行調(diào)節(jié),影響細(xì)胞內(nèi)囊泡運(yùn)輸和蛋白質(zhì)的細(xì)胞內(nèi)定位。TBC1D4參與了細(xì)胞內(nèi)多種生理過程,包括內(nèi)質(zhì)網(wǎng)到高爾基體的蛋白質(zhì)轉(zhuǎn)運(yùn)、細(xì)胞極性的建立、細(xì)胞遷移等。TBC1D4的功能異常與多種疾病有關(guān),如神經(jīng)退行性疾病、腫瘤等。研究表明,TBC1D4在腫瘤細(xì)胞中的異常表達(dá)可能與腫瘤的侵襲性和轉(zhuǎn)移性有關(guān),使其成為癌癥治療的潛在靶點(diǎn)。

熱銷產(chǎn)品

TBC1D4 Antibody (CSB-PA023218LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA023218LA01HU

Immunohistochemistry analysis of human adrenal gland tissue using CSB-PA023218LA01HU at dilution of 1:100

CSB-PA023218LA01HU

Immunocytochemistry analysis of human kidney tissue using CSB-PA023218LA01HU at dilution of 1:100

CSB-PA023218LA01HU

Immunofluorescent analysis of Hela cells using CSB-PA023218LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

TBC1D4 Antibodies

TBC1D4 for Homo sapiens (Human)

TBC1D4 Proteins

TBC1D4 Proteins for Homo sapiens (Human)