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TEAD4

TEAD4,即睪丸增強(qiáng)子相關(guān)蛋白4,別名TEF-4、RTLX3、TEAD4。它是一種由TEAD4基因編碼的轉(zhuǎn)錄因子,屬于TEA/ATTS家族成員,在多種組織中表達(dá)。TEAD4的作用機(jī)制涉及與YAP/TAZ蛋白家族成員相互作用,調(diào)控下游基因的轉(zhuǎn)錄,參與細(xì)胞增殖、遷移和組織再生等過程。TEAD4參與了多種生理和病理過程的調(diào)控,包括心臟和血管發(fā)育、肺泡形成、腫瘤發(fā)生等。TEAD4的功能異常與某些疾病有關(guān),例如在某些類型的癌癥中,TEAD4的異常激活可能促進(jìn)腫瘤細(xì)胞的增殖和侵襲,是細(xì)胞生物學(xué)和疾病研究中的一個(gè)重要分子靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Transcriptional enhancer factor TEF-3 (TEAD4), partial (CSB-BP618010HU)

驗(yàn)證數(shù)據(jù)

CSB-BP618010HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TEAD4 Antibody (CSB-PA618010LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA618010LA01HU

Western Blot
Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, K562 whole cell lysate
All lanes: TEAD4 antibody at 2.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 49, 35, 45 kDa
Observed band size: 49 kDa

CSB-PA618010LA01HU

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA618010LA01HU at dilution of 1:100

TEAD4 Antibodies

TEAD4 for Homo sapiens (Human)

TEAD4 Proteins

TEAD4 Proteins for Gallus gallus (Chicken)

TEAD4 Proteins for Homo sapiens (Human)

TEAD4 Proteins for Mus musculus (Mouse)