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TFRC

TFRC,全名為Transferrin Receptor Protein 1,是一種轉鐵蛋白受體蛋白。它位于細胞膜上,主要負責調(diào)節(jié)細胞對鐵元素的攝取。它通過結合游離鐵元素,利用循環(huán)將其傳送到細胞和組織中。一旦轉鐵蛋白與游離鐵元素結合形成轉鐵蛋白復合物,它將與細胞表面的TFRC結合。TFRC的主要功能是通過內(nèi)吞作用將轉鐵蛋白復合物帶入細胞內(nèi),以滿足細胞對鐵元素的需求,從而維持細胞的生長和代謝。 由于TFRC在細胞生長和分化中發(fā)揮著重要作用,一些藥物輸送系統(tǒng)利用TFRC在細胞膜上的表達來提供治療藥物,以增強藥物的細胞內(nèi)輸送和靶向效果。因此成為了藥物傳遞和治療靶點的潛在目標。

更多相關閱讀:轉鐵蛋白受體TFR1(TFRC):鐵穩(wěn)態(tài)關鍵成員,貧血、神經(jīng)退行性疾病、癌癥新銳靶點!

熱銷產(chǎn)品

Recombinant Human Transferrin receptor protein 1(TFRC),partial (Active) CSB-MP3648HU

驗證數(shù)據(jù)

High Purity Validated by SDS-PAGE
CSB-MP3648HU SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA
CSB-MP3648HU AC

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TFRC at 2μg/mL can bind Anti-TFRC recombinant antibody (CSB-RA023441MA1HU), the EC50 is 3.305-8.220 ng/mL.

TFRC Recombinant Monoclonal Antibody CSB-RA023441MA1HU

驗證數(shù)據(jù)

ELISA
CSB-RA023441MA1HU ELISA

The Binding Activity of Human TFRC with Anti-TFRC Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TFRC (CSB-MP3648HU) at 2 μg/mL can bind Anti-TFRC recombinant antibody , the EC50 is 3.305-8.220 ng/mL

TFRC Antibodies

TFRC for Homo sapiens (Human)

TFRC Proteins

TFRC Proteins for Equus caballus (Horse)

TFRC Proteins for Pongo abelii (Sumatran orangutan)

TFRC Proteins for Mus musculus (Mouse)

TFRC Proteins for Sus scrofa (Pig)

TFRC Proteins for Gallus gallus (Chicken)

TFRC Proteins for Rattus norvegicus (Rat)

TFRC Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

TFRC Proteins for Felis catus (Cat) (Felis silvestris catus)

TFRC Proteins for Mus musculus(Mouse)

TFRC Proteins for Homo sapiens (Human)

TFRC ELISA Kit

TFRC ELISA Kit for Mus musculus (Mouse)

TFRC ELISA Kit for Homo sapiens (Human)