TNFSF9
TNFSF9是一種膜結(jié)合蛋白,它包括一個(gè)細(xì)胞外胞糖化的結(jié)構(gòu)域,一個(gè)跨膜域以及一個(gè)細(xì)胞內(nèi)結(jié)構(gòu)域。細(xì)胞外結(jié)構(gòu)域是與其受體4-1BB(CD137)相互作用的關(guān)鍵部分。TNFSF9的主要功能是調(diào)節(jié)免疫細(xì)胞的活性,特別是T細(xì)胞的活性。當(dāng)TNFSF9與其受體4-1BB結(jié)合時(shí),它可以激活T細(xì)胞,并增強(qiáng)它們的生存、增殖和效應(yīng)功能。TNFSF9的研究已經(jīng)引起了在免疫治療領(lǐng)域的廣泛興趣。4-1BB受體的激活可以增強(qiáng)T細(xì)胞的抗腫瘤免疫反應(yīng),因此研究人員正在開(kāi)發(fā)TNFSF9相關(guān)的治療方法,包括4-1BB激動(dòng)劑。這些治療方法的目標(biāo)是增強(qiáng)免疫系統(tǒng)對(duì)癌細(xì)胞的攻擊性,提高免疫治療的療效。此外,TNFSF9的研究還有助于深入了解免疫調(diào)節(jié)的機(jī)制,可能為其他免疫性和炎癥性疾病的治療提供新的思路。
熱銷(xiāo)產(chǎn)品
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized TNFSF9 at 2 μg/ml can bind TNFRSF9(CSB-MP023984HU1), the EC50 is 2.671-3.702 ng/mL.
TNFSF9 Antibodies
TNFSF9 for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
---|---|---|---|
CSB-PA08047A0Rb | TNFSF9 Antibody | Human | ELISA, IHC, IF |
CSB-PA08047B0Rb | TNFSF9 Antibody, HRP conjugated | Human | ELISA |
CSB-PA203832 | TNFSF9 Antibody | Human | ELISA,WB,IF |
CSB-PA001424 | TNFSF9 Antibody | Human | IF, ELISA |
TNFSF9 Proteins
TNFSF9 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
---|---|---|
CSB-YP023997MO1 CSB-EP023997MO1 CSB-BP023997MO1 CSB-MP023997MO1 CSB-EP023997MO1-B |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 9 (Tnfsf9), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF023997MO | Recombinant Mouse Tumor necrosis factor ligand superfamily member 9 (Tnfsf9) | in vitro E.coli expression system |
TNFSF9 Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
---|---|---|
CSB-YP023997HU CSB-EP023997HU CSB-BP023997HU CSB-MP023997HU CSB-EP023997HU-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-RP080474h | Recombinant Human Tumor necrosis factor ligand superfamily member 9 protein (TNFSF9), partial | E.coli |
CSB-AP001961HU | Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial (Active) | E.Coli |
CSB-CF023997HU(A4) | Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9) | in vitro E.coli expression system |
CSB-MP023997HU1 | Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial (Active) | Mammalian cell |
TNFSF9 ELISA Kit
TNFSF9 ELISA Kit for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
---|---|---|---|
CSB-EL023997HU | Human Tumor necrosis factor ligand superfamily member 9(TNFSF9) ELISA kit | serum, plasma, tissue homogenates | 4.7 pg/mL |
TNFSF9 ELISA Kit for Mus musculus (Mouse)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 樣本類(lèi)型 | 靈敏度 |
---|---|---|---|
CSB-EL023997MO | Mouse Tumor necrosis factor ligand superfamily member 9(TNFSF9) ELISA kit | serum, plasma, tissue homogenates | 5.8 pg/mL |