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TNFSF9

TNFSF9是一種膜結(jié)合蛋白,它包括一個(gè)細(xì)胞外胞糖化的結(jié)構(gòu)域,一個(gè)跨膜域以及一個(gè)細(xì)胞內(nèi)結(jié)構(gòu)域。細(xì)胞外結(jié)構(gòu)域是與其受體4-1BB(CD137)相互作用的關(guān)鍵部分。TNFSF9的主要功能是調(diào)節(jié)免疫細(xì)胞的活性,特別是T細(xì)胞的活性。當(dāng)TNFSF9與其受體4-1BB結(jié)合時(shí),它可以激活T細(xì)胞,并增強(qiáng)它們的生存、增殖和效應(yīng)功能。TNFSF9的研究已經(jīng)引起了在免疫治療領(lǐng)域的廣泛興趣。4-1BB受體的激活可以增強(qiáng)T細(xì)胞的抗腫瘤免疫反應(yīng),因此研究人員正在開(kāi)發(fā)TNFSF9相關(guān)的治療方法,包括4-1BB激動(dòng)劑。這些治療方法的目標(biāo)是增強(qiáng)免疫系統(tǒng)對(duì)癌細(xì)胞的攻擊性,提高免疫治療的療效。此外,TNFSF9的研究還有助于深入了解免疫調(diào)節(jié)的機(jī)制,可能為其他免疫性和炎癥性疾病的治療提供新的思路。

熱銷(xiāo)產(chǎn)品

Recombinant Human Tumor necrosis factor ligand superfamily member 9(TNFSF9),partial (Active) CSB-MP023997HU1

驗(yàn)證數(shù)據(jù)

SDS
CSB-MP023997HU1-SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ELISA
High Purity Validated of CSB-MP023997HU1

Activity: Measured by its binding ability in a functional ELISA. Immobilized TNFSF9 at 2 μg/ml can bind TNFRSF9(CSB-MP023984HU1), the EC50 is 2.671-3.702 ng/mL.


TNFSF9 Antibodies

TNFSF9 for Homo sapiens (Human)

TNFSF9 Proteins

TNFSF9 Proteins for Mus musculus (Mouse)

TNFSF9 Proteins for Homo sapiens (Human)

TNFSF9 ELISA Kit

TNFSF9 ELISA Kit for Homo sapiens (Human)

TNFSF9 ELISA Kit for Mus musculus (Mouse)