ZAP70
ZAP70,即ζ鏈相關(guān)激酶70,別名SRK、STD、TZK等。它來源于人類基因表達(dá),編碼一種屬于酪氨酸激酶家族的蛋白質(zhì)。ZAP70在T細(xì)胞和NK細(xì)胞中表達(dá),主要參與T細(xì)胞受體(TCR)的信號轉(zhuǎn)導(dǎo)途徑,通過其酪氨酸激酶活性激活T細(xì)胞和NK細(xì)胞的免疫活性。在生物學(xué)意義上,ZAP70的正常功能對于T細(xì)胞的正常發(fā)育和免疫應(yīng)答至關(guān)重要。此外,ZAP70的異常表達(dá)與某些疾病如慢性淋巴細(xì)胞白血病(CLL)的預(yù)后不良密切相關(guān),因此具有重要的臨床診斷和治療指導(dǎo)價值。
熱銷產(chǎn)品
Recombinant Human Tyrosine-protein kinase ZAP-70 (ZAP70) (CSB-EP026303HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數(shù)據(jù)
Western Blot analysis of 293 cells using ZAP-70 Polyclonal Antibody
ZAP70 Antibodies
ZAP70 for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA026303GA01HU | ZAP70 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA969675 | Phospho-ZAP70 (Tyr319) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA280694 | Phospho-ZAP70 (Tyr493) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA181899 | ZAP70 (Ab-319) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA447684 | ZAP70 (Ab-493) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA060096 | Phospho-ZAP70 (Y319) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA060097 | Phospho-ZAP70 (Y493) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA060098 | Phospho-ZAP70 (Y292) Antibody | Human,Mouse | WB, ELISA |
CSB-PA060099 | Phospho-ZAP70 (Y315) Antibody | Human,Mouse | WB, IHC, ELISA |
CSB-PA060100 | ZAP70 Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
CSB-PA060101 | ZAP70 Antibody | Human,Mouse | IHC, ELISA |
CSB-PA060102 | ZAP70 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA060103 | ZAP70 Antibody | Human,Mouse | WB, ELISA |
CSB-PA823016 | ZAP70 Antibody | Human | IHC,ELISA |
ZAP70 for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA026303LA01MO | Zap70 Antibody | Mouse, Human | ELISA, WB, IF |
ZAP70 Proteins
ZAP70 Proteins for Homo sapiens (Human)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP026303HU CSB-BP026303HU CSB-MP026303HU CSB-EP026303HU-B |
Recombinant Human Tyrosine-protein kinase ZAP-70 (ZAP70) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP026303HU | Recombinant Human Tyrosine-protein kinase ZAP-70 (ZAP70) | E.coli |
ZAP70 Proteins for Mus musculus (Mouse)
產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP026303MO CSB-EP026303MO CSB-BP026303MO CSB-MP026303MO CSB-EP026303MO-B |
Recombinant Mouse Tyrosine-protein kinase ZAP-70 (Zap70) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |