ZNRF3
ZNRF3（Zinc and Ring Finger 3）屬于RING（Really Interesting New Gene）指環(huán)蛋白家族，它包含一個RING結構域，這是一個特定類型的結構域，具有E3泛素連接酶活性。ZNRF3的主要功能之一是調節(jié)細胞膜上受體和蛋白質的穩(wěn)定性。它通過將泛素分子附加到目標蛋白質上，標記它們以進行降解。這個過程被稱為泛素化，是細胞對于調控蛋白質水平和信號通路的重要機制之一。在癌癥研究領域，ZNRF3與Wnt信號通路的調控有關，該信號通路在多種癌癥中起關鍵作用。
熱銷產品
Recombinant Human E3 ubiquitin-protein ligase ZNRF3(ZNRF3),partial (Active) CSB-MP890933HU
驗證數據
SDS
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ELISA
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ZNRF3 at 5 μg/ml can bind Human RSPO2 (CSB-MP751021HU1(M)), the EC50 is 5.091-6.991 ng/mL.
ZNRF3 Antibodies
ZNRF3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA890933HA01HU | ZNRF3 Antibody | Human | ELISA, IF |
| CSB-PA890933HB01HU | ZNRF3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA890933HC01HU | ZNRF3 Antibody, FITC conjugated | Human | |
| CSB-PA890933HD01HU | ZNRF3 Antibody, Biotin conjugated | Human | ELISA |
ZNRF3 Proteins
ZNRF3 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP716332MO CSB-EP716332MO CSB-BP716332MO CSB-MP716332MO CSB-EP716332MO-B |
Recombinant Mouse Zinc/RING finger protein 3 (Znrf3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ZNRF3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP890933HU-B |
Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial | In Vivo Biotinylation in E.coli |
| CSB-EP890933HU | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial | E.coli |
| CSB-EP890933HUe1 | Recombinant Human Zinc/RING finger protein 3 (ZNRF3),Partial | E.coli |
| CSB-BP890933HU | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial | Baculovirus |
| CSB-YP890933HU | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial | Yeast |
| CSB-MP890933HU | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial (Active) | Mammalian cell |
