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ARFIP1 Antibody

  • 中文名稱：
    ARFIP1兔多克隆抗體
  • 貨號：
    CSB-PA002002GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ARFIP1
  • 別名：
    ADP ribosylation factor interacting protein 1 antibody; ADP-ribosylation factor-interacting protein 1 antibody; Arfaptin antibody; Arfaptin-1 antibody; ARFIP 1 antibody; Arfip1 antibody; ARFP1_HUMAN antibody; HSU52521 antibody; MGC117369 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ARFIP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in controlling biogenesis of secretory granules at the trans-Golgi network. Mechanisitically, binds ARF-GTP at the neck of a growing secretory granule precursor and forms a protective scaffold. Once the granule precursor has been completely loaded, active PRKD1 phosphorylates ARFIP1 and releases it from ARFs. In turn, ARFs induce fission. Through this mechanism, ensures proper secretory granule formation at the Golgi of pancreatic beta cells.
  • 基因功能參考文獻：
    1. inhibits ADP-ribosylation factor-dependent matrix metalloproteinase-9 secretion induced by phorbol ester in fibrosarcoma cells PMID: 12606037
  • 亞細胞定位：
    Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
  • 組織特異性：
    Ubiquitously expressed. Higher levels in liver, pancreas, placenta, skeletal muscle and heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21496

    OMIM: 605928

    KEGG: hsa:27236

    STRING: 9606.ENSP00000296557

    UniGene: Hs.416089