Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ARFIP1 Antibody

ARFIP1 Antibody

  • 中文名稱：
    ARFIP1兔多克隆抗體
  • 貨號：
    CSB-PA984263
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from Jurkat cells, using ARFIP1 antibody.
    • Immunofluorescence analysis of A549 cells, using ARFIP1 antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ARFIP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ARFIP1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human ARFIP1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IF 1:100-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Plays a role in controlling biogenesis of secretory granules at the trans-Golgi network. Mechanisitically, binds ARF-GTP at the neck of a growing secretory granule precursor and forms a protective scaffold. Once the granule precursor has been completely loaded, active PRKD1 phosphorylates ARFIP1 and releases it from ARFs. In turn, ARFs induce fission. Through this mechanism, ensures proper secretory granule formation at the Golgi of pancreatic beta cells.
  • 基因功能參考文獻(xiàn)：
    1. inhibits ADP-ribosylation factor-dependent matrix metalloproteinase-9 secretion induced by phorbol ester in fibrosarcoma cells PMID: 12606037
  • 亞細(xì)胞定位：
    Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
  • 組織特異性：
    Ubiquitously expressed. Higher levels in liver, pancreas, placenta, skeletal muscle and heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21496

    OMIM: 605928

    KEGG: hsa:27236

    STRING: 9606.ENSP00000296557

    UniGene: Hs.416089