FMO5 Antibody
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中文名稱:FMO5兔多克隆抗體
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貨號(hào):CSB-PA008751ESR1HU
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規(guī)格:¥440
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促銷:
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) FMO5 Polyclonal antibody
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Uniprot No.:
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基因名:FMO5
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別名:Dimethylaniline monooxygenase [N oxide forming] 5 antibody; Dimethylaniline monooxygenase [N-oxide-forming] 5 antibody; Dimethylaniline oxidase 5 antibody; FMO 5 antibody; FMO5 antibody; FMO5_HUMAN antibody; Hepatic flavin containing monooxygenase 5 antibody; Hepatic flavin-containing monooxygenase 5 antibody
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宿主:Rabbit
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反應(yīng)種屬:Human
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免疫原:Recombinant Human Dimethylaniline monooxygenase [N-oxide-forming] 5 protein (1-285AA)
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免疫原種屬:Homo sapiens (Human)
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標(biāo)記方式:Non-conjugated
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:Antigen Affinity Purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA, IHC
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推薦稀釋比:
Application Recommended Dilution IHC 1:20-1:200 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Acts as Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms (Probable). Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects.
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基因功能參考文獻(xiàn):
- Report relatively stable FMO5 expression throughout development. PMID: 26839369
- Nabumetone and pentoxifylline, two widely used pharmaceuticals, were thereby demonstrated to be efficiently oxidized in vitro by FMO5 to the corresponding acetate esters with high selectivity. PMID: 28783300
- absence of the typical characteristic sequence motifs sets human FMO5 apart from all characterized Baeyer-Villiger mono-oxygenases so far. These findings open new perspectives in human oxidative metabolism PMID: 26771671
- fmo5 displayed a significant, dominant liver-specific mRNA profile. PMID: 16183778
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亞細(xì)胞定位:Microsome membrane. Endoplasmic reticulum membrane.
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蛋白家族:FMO family
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組織特異性:Expressed in fetal and adult liver.
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數(shù)據(jù)庫鏈接:
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