HSD17B14 Antibody

Datasheet

產(chǎn)品詳情

Uniprot No.：

Q9BPX1
基因名：

HSD17B14
別名：

HSD17B14 antibody; DHRS10 antibody; SDR3 antibody; SDR47C1 antibody; UNQ502/PRO47417-beta-hydroxysteroid dehydrogenase 14 antibody; 17-beta-HSD 14 antibody; EC 1.1.1.- antibody; 17-beta-hydroxysteroid dehydrogenase DHRS10 antibody; Dehydrogenase/reductase SDR family member 10 antibody; Retinal short-chain dehydrogenase/reductase retSDR3 antibody; Short chain dehydrogenase/reductase family 47C member 1 antibody
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human HSD17B14
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

功能：

Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).
基因功能參考文獻(xiàn)：
1. Results show that tumoural expression levels of 17betaHSD14 can predict the outcome of adjuvant tamoxifen treatment in terms of local recurrence-free survival in patients with lymph node-negative ER+ breast cancer. PMID: 22792371
2. crystal structure of the DHRS10 apoenzyme exhibits secondary structure of the SDR (short-chain dehydrogenase/reductase) family PMID: 17067289
亞細(xì)胞定位：

Cytoplasm.
蛋白家族：

Short-chain dehydrogenases/reductases (SDR) family
組織特異性：

Highly expressed in brain, placenta, liver and kidney.
數(shù)據(jù)庫鏈接：

HGNC: 23238

OMIM: 612832

KEGG: hsa:51171

STRING: 9606.ENSP00000263278

UniGene: Hs.18788