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HSD17B14 Antibody

  • 中文名稱：
    HSD17B14兔多克隆抗體
  • 貨號(hào)：
    CSB-PA077030
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA077030(HSD17B14 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA077030(HSD17B14 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse kidney tissue, Primary antibody: CSB-PA077030(HSD17B14 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    HSD17B14
  • 別名：
    HSD17B14 antibody; DHRS10 antibody; SDR3 antibody; SDR47C1 antibody; UNQ502/PRO47417-beta-hydroxysteroid dehydrogenase 14 antibody; 17-beta-HSD 14 antibody; EC 1.1.1.- antibody; 17-beta-hydroxysteroid dehydrogenase DHRS10 antibody; Dehydrogenase/reductase SDR family member 10 antibody; Retinal short-chain dehydrogenase/reductase retSDR3 antibody; Short chain dehydrogenase/reductase family 47C member 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human HSD17B14
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).
  • 基因功能參考文獻(xiàn)：
    1. Results show that tumoural expression levels of 17betaHSD14 can predict the outcome of adjuvant tamoxifen treatment in terms of local recurrence-free survival in patients with lymph node-negative ER+ breast cancer. PMID: 22792371
    2. crystal structure of the DHRS10 apoenzyme exhibits secondary structure of the SDR (short-chain dehydrogenase/reductase) family PMID: 17067289
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Short-chain dehydrogenases/reductases (SDR) family
  • 組織特異性：
    Highly expressed in brain, placenta, liver and kidney.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 23238

    OMIM: 612832

    KEGG: hsa:51171

    STRING: 9606.ENSP00000263278

    UniGene: Hs.18788