NEK11 Antibody
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中文名稱:NEK11兔多克隆抗體
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貨號:CSB-PA015698GA01HU
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規(guī)格:¥3,900
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其他:
產(chǎn)品詳情
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Uniprot No.:
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基因名:NEK11
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別名:4932416N14Rik antibody; FLJ23495 antibody; NEK11 antibody; NEK11_HUMAN antibody; NEK11S/L antibody; Never in mitosis A-related kinase 11 antibody; NIMA (never in mitosis gene a) related kinase 11 antibody; NIMA (never in mitosis gene a)- related kinase 11 antibody; NIMA related kinase 11L antibody; NIMA related kinase 11S antibody; NIMA-related kinase 11 antibody; NimA-related protein kinase 11 antibody; Serine/threonine-protein kinase Nek11 antibody
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宿主:Rabbit
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反應種屬:Human,Mouse,Rat
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免疫原:Human NEK11
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免疫原種屬:Homo sapiens (Human)
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抗體亞型:IgG
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純化方式:Antigen Affinity Purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式:Liquid
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應用范圍:ELISA,WB
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Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關產(chǎn)品
靶點詳情
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功能:Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
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基因功能參考文獻:
- contributes to response of colorectal cancer cells to genotoxic agents and is essential for survival either with or without exposure to DNA damage PMID: 26501353
- Results show that downregulation of NEK11 in drug resistant cells might contribute to drug resistance in ovarian cancer. PMID: 24969318
- NEK11 controls degradation of CDC25A by directly phosphorylating CDC25A on residues whose phosphorylation is required for beta-TrCP mediated CDC25A polyubiquitylation and degradation. PMID: 20090422
- Nek11 has a role in the S-phase checkpoint downstream of the caffeine-sensitive pathway PMID: 12154088
- Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells PMID: 15161910
- NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint. PMID: 19734889
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亞細胞定位:Nucleus. Nucleus, nucleolus.
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蛋白家族:Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily
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組織特異性:Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
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數(shù)據(jù)庫鏈接:
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