RAB3GAP2 Antibody
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中文名稱:RAB3GAP2兔多克隆抗體
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貨號(hào):CSB-PA215524
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規(guī)格:¥2024
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圖片:
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其他:
產(chǎn)品詳情
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產(chǎn)品名稱:Rabbit anti-Homo sapiens (Human) RAB3GAP2 Polyclonal antibody
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Uniprot No.:
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基因名:RAB3GAP2
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宿主:Rabbit
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反應(yīng)種屬:Human,Mouse
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免疫原:Synthesized peptide derived from internal of Human.
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免疫原種屬:Homo sapiens (Human)
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克隆類型:Polyclonal
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純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:It differs from different batches. Please contact us to confirm it.
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產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA,WB,IHC
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:3000 IHC 1:50-1:100 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
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基因功能參考文獻(xiàn):
- functionally severe RAB3GAP2 mutations cause Warburg Micro syndrome while hypomorphic RAB3GAP2 mutations can result in the milder Martsolf phenotype PMID: 20967465
- Data show that at chemical synapses, Rab3 performs specific functions in synpatic vesicle exocytosis. PMID: 18485483
- KIF1Bbeta- and KIF1A-mediated axonal transport of presynaptic regulator RAB3GAP2 occurs in a GTP-dependent manner through MADD. PMID: 18849981
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相關(guān)疾病:Martsolf syndrome (MARTS); Warburg micro syndrome 2 (WARBM2)
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亞細(xì)胞定位:Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction.
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蛋白家族:Rab3-GAP regulatory subunit family
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組織特異性:Ubiquitous.
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數(shù)據(jù)庫(kù)鏈接:
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