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Recombinant Danio rerio Non-homologous end-joining factor 1 (nhej1)

  • 中文名稱：
    斑馬魚nhej1重組蛋白
  • 貨號：
    CSB-YP747354DIL
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    斑馬魚nhej1重組蛋白
  • 貨號：
    CSB-EP747354DIL
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    斑馬魚nhej1重組蛋白
  • 貨號：
    CSB-EP747354DIL-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    斑馬魚nhej1重組蛋白
  • 貨號：
    CSB-BP747354DIL
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    斑馬魚nhej1重組蛋白
  • 貨號：
    CSB-MP747354DIL
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    nhej1
  • Uniprot No.：
  • 別名：
    nhej1; xlf; zgc:85657; Non-homologous end-joining factor 1; Protein cernunnos; XRCC4-like factor
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-309
  • 氨基酸序列
    MEAVLSALPW VPVNISGSDL LAKAWFGDSQ YRVLLTDLST VWEEEMSTDD IQSRAQDLNK RLRAPAQAFF SHLCSVARPC FSGLDEDQIS AAQAALEQHG ESLTVKLKSE LAGLPFYWEF RCTTTPVAVV CRQLVRPLLA MTLVLQRQAE DLAALLARKD AEIQDYQENG AVLSRARLQT EPFEVHQYKE NFITQILPQM NVTLDSLGFD SELQALYMAV NSGKTGRKRK HSPDSSPAAQ ENHITDHQHI SESTDVGPSL ASQEHNNAKE SGRSQVANSQ QTLPLSSTAG SEDRSTSRAK KKKAVGLFR
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    DNA repair protein involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair and V(D)J recombination. Plays a key role in NHEJ by promoting the ligation of various mismatched and non-cohesive ends. Associates with xrcc4 to form alternating helical filaments that bridge DNA and act like a bandage, holding together the broken DNA until it is repaired. The xrcc4-nhej1/xlf subcomplex binds to the DNA fragments of a DSB in a highly diffusive manner and robustly bridges two independent DNA molecules, holding the broken DNA fragments in close proximity to one other. The mobility of the bridges ensures that the ends remain accessible for further processing by other repair factors.
  • 亞細(xì)胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    XLF family
  • 數(shù)據(jù)庫鏈接：