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  4. Recombinant Danio rerio Programmed cell death protein 10-A (pdcd10a)

Recombinant Danio rerio Programmed cell death protein 10-A (pdcd10a)

  • 中文名稱(chēng)：
    斑馬魚(yú)pdcd10a重組蛋白
  • 貨號(hào)：
    CSB-YP740786DIL
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    斑馬魚(yú)pdcd10a重組蛋白
  • 貨號(hào)：
    CSB-EP740786DIL
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    斑馬魚(yú)pdcd10a重組蛋白
  • 貨號(hào)：
    CSB-EP740786DIL-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    斑馬魚(yú)pdcd10a重組蛋白
  • 貨號(hào)：
    CSB-BP740786DIL
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    斑馬魚(yú)pdcd10a重組蛋白
  • 貨號(hào)：
    CSB-MP740786DIL
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    pdcd10a
  • Uniprot No.：
  • 別名：
    pdcd10a; pdcd10; si:ch211-167c22.5; Programmed cell death protein 10-A
  • 種屬：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-210
  • 氨基酸序列
    MTMEEMKNEA DATSMVSMTL YAVMYPVFNE LESVNLSAAQ TLRAAFKKAE KENPGLTQDI IMKILEKKNV EINFTESLLR MAADDVEEYM IDRPEREFQD LNERARALKQ ILSKIPDEIN DRVRFLQTIK DIASAIKELL DTVNNVFKKY QYQNRRALEH QKKEFVKHSK SFSDTLKTYF KDGKAINVFA SANRLIHQTN LILQTFKTVA
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. Required for normal cardiovascular development.
  • 基因功能參考文獻(xiàn)：
    1. CCM3 plays a role distinct from CCM1/2 in Cerebral cavernous malformations pathogenesis, and acts via GCKIII activity to regulate cranial vasculature integrity and development. PMID: 22182521
    2. Sequence conservation and binding studies suggest that CCM3 may preferentially heterodimerize with GCKIII proteins through a manner structurally analogous to that employed for CCM3 homodimerization. PMID: 21561863
    3. The newly mapped STK25 and MST4 interaction domain within the CCM3 protein plays a crucial role for vascular development in zebrafish. PMID: 19370760
  • 亞細(xì)胞定位：
    Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    PDCD10 family
  • 數(shù)據(jù)庫(kù)鏈接：