Recombinant Human AMP deaminase 1 (AMPD1)
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中文名稱:Recombinant Human AMP deaminase 1(AMPD1),Yeast
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貨號:CSB-YP001680HU
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規(guī)格:
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來源:Yeast
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其他:
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中文名稱:Recombinant Human AMP deaminase 1(AMPD1),Yeast
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貨號:CSB-EP001680HU
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規(guī)格:
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來源:E.coli
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其他:
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中文名稱:Recombinant Human AMP deaminase 1(AMPD1),Yeast
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貨號:CSB-EP001680HU-B
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規(guī)格:
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來源:E.coli
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共軛:Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他:
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中文名稱:Recombinant Human AMP deaminase 1(AMPD1),Yeast
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貨號:CSB-BP001680HU
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規(guī)格:
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來源:Baculovirus
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其他:
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中文名稱:Recombinant Human AMP deaminase 1(AMPD1),Yeast
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貨號:CSB-MP001680HU
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規(guī)格:
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來源:Mammalian cell
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其他:
產(chǎn)品詳情
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純度:>85% (SDS-PAGE)
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基因名:AMPD1
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Uniprot No.:
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別名:AMPD1AMP deaminase 1; EC 3.5.4.6; AMP deaminase isoform M; Myoadenylate deaminase
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種屬:Homo sapiens (Human)
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蛋白長度:Full length protein
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表達區(qū)域:1-780
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氨基酸序列MNVRIFYSVS QSPHSLLSLL FYCAILESRI SATMPLFKLP AEEKQIDDAM RNFAEKVFAS EVKDEGGRQE ISPFDVDEIC PISHHEMQAH IFHLETLSTS TEARRKKRFQ GRKTVNLSIP LSETSSTKLS HIDEYISSSP TYQTVPDFQR VQITGDYASG VTVEDFEIVC KGLYRALCIR EKYMQKSFQR FPKTPSKYLR NIDGEAWVAN ESFYPVFTPP VKKGEDPFRT DNLPENLGYH LKMKDGVVYV YPNEAAVSKD EPKPLPYPNL DTFLDDMNFL LALIAQGPVK TYTHRRLKFL SSKFQVHQML NEMDELKELK NNPHRDFYNC RKVDTHIHAA ACMNQKHLLR FIKKSYQIDA DRVVYSTKEK NLTLKELFAK LKMHPYDLTV DSLDVHAGRQ TFQRFDKFND KYNPVGASEL RDLYLKTDNY INGEYFATII KEVGADLVEA KYQHAEPRLS IYGRSPDEWS KLSSWFVCNR IHCPNMTWMI QVPRIYDVFR SKNFLPHFGK MLENIFMPVF EATINPQADP ELSVFLKHIT GFDSVDDESK HSGHMFSSKS PKPQEWTLEK NPSYTYYAYY MYANIMVLNS LRKERGMNTF LFRPHCGEAG ALTHLMTAFM IADDISHGLN LKKSPVLQYL FFLAQIPIAM SPLSNNSLFL EYAKNPFLDF LQKGLMISLS TDDPMQFHFT KEPLMEEYAI AAQVFKLSTC DMCEVARNSV LQCGISHEEK VKFLGDNYLE EGPAGNDIRR TNVAQIRMAY RYETWCYELN LIAEGLKSTE
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蛋白標簽:Tag?type?will?be?determined?during?the?manufacturing?process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
產(chǎn)品提供形式:Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
復溶:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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儲存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質(zhì)期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期:Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項:Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet :Please contact us to get it.
相關(guān)產(chǎn)品
靶點詳情
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功能:AMP deaminase plays a critical role in energy metabolism.
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基因功能參考文獻:
- T allele of AMPD1 gene C34T polymorphism may be correlated with LVEF, LVEDD and SBP, which plays a protective role in the cardiac functions and blood pressure in cardiovascular disease patients. PMID: 28673246
- The metabolic-chronotropic response is decreased in skeletal muscle MAD deficiency, suggesting a biological mechanism by which AMPD1 gene exerts cardiac effect PMID: 29095874
- Variations in AMPD1, CPT2, and PGYM genes are not associated with the onset, susceptibility, or severity of chronic fatigue syndrome. PMID: 27525900
- Common polymorphism of the AMPD1 gene (C34T) is strongly associated with essential hypertension. PMID: 27323204
- AMPD1 could have a profound influence on cholinergic neurotransmission and sleep; further studies are mandatory PMID: 26439223
- AMPD1 34C>T variant is associated with higher infection susceptibility to community acquired pneumonia but not to ventilator associated pneumonia in sepsis pateints PMID: 26529652
- Mutational variants in AMPD1 contribute to autism risk in Han Chinese population, via mitochondria dysfunction and cell necrosis. PMID: 25155876
- The best response to creatine in terms of physical performance was presented by AMPD1 CC genotype. PMID: 25665401
- The present study demonstrated a positive effect of C34T AMPD1 gene polymorphism in aortic stiffness and in inflammatory status in a high risk population of CAD subjects. PMID: 24508110
- Our other studies on the metabolic impact of AMPD1 C34T mutation revealed decrease in AMPD activity. PMID: 24431031
- Alpinists show significantly higher frequencies of T allele compared to controls. PMID: 24058088
- AMPD1 gene polymorphism C34T can be considered as a marker of liability to the high-speed and strength muscular activity. PMID: 23486588
- In a study of a Spanish and 2 North African cohorts, frequency of the AMPD1 C34T mutation was lower in Berbers compared with the Alpujarra cohort. The GDF8 K153R substitution showed little variability among the three cohorts. PMID: 22324844
- There was a lower frequency of the AMPD1 exon 2 T34 allele in elite Polish power-oriented athletes. The data suggested that the C allele may help athletes to attain elite status in power-oriented sports. PMID: 22017426
- The researchers found evidence that the T allele polymorphism of the AMPD1 gene is associated with negative factor in athletic performance PMID: 22105616
- AMPD1 gene mutations are associated with obesity and diabetes in Polish patients with cardiovascular diseases. PMID: 21108053
- some physico-chemical properties of AMP-deaminase isolated from cardiac muscle of a 10-year-old boy heterozygote for this mutation PMID: 20544536
- A G468T AMPD1 mutant allele contributes to the high incidence of myoadenylate deaminase deficiency in the Caucasian population. PMID: 12117480
- Significantly higher frequency of mutation among donors with healthy hearts used for transplantation. Lower frequency in dysfunctional donor hearts. Frequency of C34T mutation in chronic heart failure was not different. (Review) PMID: 15239633
- The AMPD1 C34T polymorphism influences transplant-free cardiovascular survival in the setting of ischemic left ventricular dysfunction. PMID: 15309698
- Primary myoadenylate-deaminase deficiency was diagnosed based upon elevated creatine-kinase, absent staining for MAD on muscle biopsy, markedly reduced MAD activity in the muscle homogenate, and C34T mutation within exon 2 of AMPD1 gene. PMID: 15368811
- In conclusion, although the frequency distribution of the mutant T allele of the AMPD1 genotype is lower in Caucasian elite endurance athletes than in controls, the C34T mutation does not significantly impair endurance performance. PMID: 15677729
- In this study, the metabolic clearance rate of insulin was associated with AMPD1 SNPs and haplotypes. PMID: 15793265
- a C34T mutation in AMP deaminase is found more frequently in healthy donor hearts than in healthy controls or donors with failing hearts PMID: 16021915
- the AMPD1 mutation decreases the activity of AMP-deaminase in the heart without changing the activity of any other enzymes of adenine nucleotide metabolism PMID: 16021918
- The interpretation of the significance of these observations suggests a physiological mutual dependence between skeletal muscle HPRG and AMPD polypeptides with regard to their stability. PMID: 16570231
- Genes are associated with good clinical response of rheumatoid arthritis to methotrexate treatment. PMID: 16947783
- We did not demonstrate any effect of the C34T polymorphism of the AMPD1 gene on major congestive heart failure parameters and on survival. PMID: 16996850
- The 34C > T variant of AMPD1 augments vasodilation and reduces tissue injury in response to forearm ischaemia. These mechanisms could contribute to the survival benefit of cardiovascular patients with this variant allele. PMID: 17376785
- Reveals a functional role for skeletal muscle AMPD1 enzyme in sprint exercise. PMID: 17463303
- C34T and G468T variations in the adenosine monophosphate deaminase-1 (AMPD1) gene were associated with intima-media thickness of the carotid and brachial artery, endothelial function of the brachial artery in patients with coronary heart disease. PMID: 17565237
- Results suggest a better circulatory adaptation to exercise in individuals with diminished AMPD1 activity, probably due to an AMPD1 genotype-dependent increase in adenosine formation. PMID: 18224333
- may control the systemic metabolic status by changing AMPK activity through the AMP level. PMID: 18409530
- This is a first report evidencing the pattern of AMPD genes expression in neoplastic human liver. PMID: 18493842
- C34T AMPD1 polymorphism may be associated with reduced frequency of obesity in coronary artery disease(CAD) patients and of hyperglycaemia and diabetes in both CAD and heart failure patients. PMID: 18855224
- We found statistical significance for ACE ID and II genotypes in soccer players than in runners; Statistical significance was also reached for AMPD1 (with higher frequency of CT genotype in soccer players than in runners [chi(2)((2))=7.538, P=0.006]) PMID: 19277943
- Possession of AMPD1 T allele is associated with decreased inotropic requirements before heart donation. Incidence of graft dysfunction was significantly higher in recipients who received AMPD1 T-allele-possessing organs resulting in worse 1-year survival. PMID: 19427446
- Observational study of gene-disease association, pharmacogenomic / toxicogenomic, and genetic testing. (HuGE Navigator) PMID: 17530705
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相關(guān)疾?。?/div>Myopathy due to myoadenylate deaminase deficiency (MMDD)蛋白家族:Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family數(shù)據(jù)庫鏈接:
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