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  4. Recombinant Human Abhydrolase domain-containing protein 10, mitochondrial (ABHD10)

Recombinant Human Abhydrolase domain-containing protein 10, mitochondrial (ABHD10)

  • 中文名稱：
    Recombinant Human Abhydrolase domain-containing protein 10, mitochondrial(ABHD10),Yeast
  • 貨號：
    CSB-YP865140HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Abhydrolase domain-containing protein 10, mitochondrial(ABHD10),Yeast
  • 貨號：
    CSB-EP865140HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Abhydrolase domain-containing protein 10, mitochondrial(ABHD10),Yeast
  • 貨號：
    CSB-EP865140HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Abhydrolase domain-containing protein 10, mitochondrial(ABHD10),Yeast
  • 貨號：
    CSB-BP865140HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Abhydrolase domain-containing protein 10, mitochondrial(ABHD10),Yeast
  • 貨號：
    CSB-MP865140HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ABHD10
  • Uniprot No.：
  • 別名：
    Abhd10; ABHDA_HUMAN; Abhydrolase domain containing 10; Abhydrolase domain-containing protein 10; Abhydrolase domain-containing protein 10; mitochondrial; Alpha/beta hydrolase domain containing protein 10 mitochondrial; mitochondrial; Mycophenolic acid acyl glucuronide esterase mitochondrial
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    53-306
  • 氨基酸序列
    TSLSFLNR PDLPNLAYKK LKGKSPGIIF IPGYLSYMNG TKALAIEEFC KSLGHACIRF DYSGVGSSDG NSEESTLGKW RKDVLSIIDD LADGPQILVG SSLGGWLMLH AAIARPEKVV ALIGVATAAD TLVTKFNQLP VELKKEVEMK GVWSMPSKYS EEGVYNVQYS FIKEAEHHCL LHSPIPVNCP IRLLHGMKDD IVPWHTSMQV ADRVLSTDVD VILRKHSDHR MREKADIQLL VYTIDDLIDK LSTIVN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins. Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability. Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate.
  • 基因功能參考文獻：
    1. Which potently inhibited ABHD10 activity. PMID: 25217485
    2. mitochondrial localization of rat Abhd10 PMID: 21078990
    3. ABHD10 is responsible for deglucuronidation of mycophenolic acid acyl-glucuronide in liver. PMID: 22294686
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    AB hydrolase superfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25656

    KEGG: hsa:55347

    STRING: 9606.ENSP00000273359

    UniGene: Hs.477115