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  4. Recombinant Human UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (SLC35D2), partial

Recombinant Human UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (SLC35D2), partial

  • 中文名稱：
    人SLC35D2重組蛋白
  • 貨號：
    CSB-YP765728HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SLC35D2重組蛋白
  • 貨號：
    CSB-EP765728HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SLC35D2重組蛋白
  • 貨號：
    CSB-EP765728HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SLC35D2重組蛋白
  • 貨號：
    CSB-BP765728HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SLC35D2重組蛋白
  • 貨號：
    CSB-MP765728HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC35D2
  • Uniprot No.：
  • 別名：
    Fringe connection; HFRC 1; Hfrc; HFRC1; Homolog of Fringe connection protein 1; MGC117215; MGC142139; Nucleotide sugar transporter UGTrel8; S35D2_HUMAN; SLC35D2; Solute carrier family 35 member D2; SQV 7L; SQV7-like protein; SQV7L; UDP N acetylglucosamine transporter; UDP-galactose transporter-related protein 8; UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter; UGTrel 8; UGTrel8
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Antiporter transporting nucleotide sugars such as UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling.
  • 基因功能參考文獻：
    1. HFRC1 takes part in the synthesis of heparan sulfate by regulating the level of UDP-GlcNAc, a donor substrate for the heparan sulfate synthases PMID: 15082721
    2. HFRC1 was overexpressed in human bronchial epithelial cells and was shown to localize in the Golgi and to enhance the surface expression of N-acetylglucosamine-rich glycans. PMID: 19276090
  • 亞細胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    TPT transporter family, SLC35D subfamily
  • 組織特異性：
    Highly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20799

    OMIM: 609182

    KEGG: hsa:11046

    STRING: 9606.ENSP00000253270

    UniGene: Hs.494556