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Recombinant Pig Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1)

  • 中文名稱：
    斯克羅法SUCLG1重組蛋白
  • 貨號(hào)：
    CSB-YP022919PI
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    斯克羅法SUCLG1重組蛋白
  • 貨號(hào)：
    CSB-EP022919PI
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    斯克羅法SUCLG1重組蛋白
  • 貨號(hào)：
    CSB-EP022919PI-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    斯克羅法SUCLG1重組蛋白
  • 貨號(hào)：
    CSB-BP022919PI
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    斯克羅法SUCLG1重組蛋白
  • 貨號(hào)：
    CSB-MP022919PI
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SUCLG1
  • Uniprot No.：
  • 別名：
    SUCLG1; Succinate--CoA ligase [ADP/GDP-forming] subunit alpha; mitochondrial; EC 6.2.1.4; EC 6.2.1.5; Succinyl-CoA synthetase subunit alpha; SCS-alpha
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Full length protein
  • 表達(dá)區(qū)域：
    41-346
  • 氨基酸序列
    CSYTASRKHL YVDKNTKVIC QGFTGKQGTF HSQQALEYGT NLVGGTTPGK GGKTHLGLPV FNTVKEAKEQ TGATASVIYV PPPFAAAAIN EAIDAEVPLV VCITEGIPQQ DMVRVKHRLL RQGKTRLIGP NCPGVINPGE CKIGIMPGHI HKKGRIGIVS RSGTLTYEAV HQTTQVGLGQ SLCVGIGGDP FNGTDFTDCL EIFLNDPATE GIILIGEIGG NAEENAAEFL KQHNSGPKSK PVVSFIAGLT APPGRRMGHA GAIIAGGKGG AKEKITALQS AGVVVSMSPA QLGTTIYKEF EKRKML
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  • 基因功能參考文獻(xiàn)：
    1. Pig GTP-specific succinyl-CoA synthetase was crystallized in the presence of succinate, magnesium ions and CoA, and the structure of the complex was determined by X-ray crystallography to 2.2 A resolution. Succinate binds in the carboxy-terminal domain of the beta-subunit. PMID: 27487822
    2. Structure of GTP-specific succinyl-CoA synthetase subunits in complex with CoA has been resolved. PMID: 26249701
    3. succinyl-CoA synthetase is able to protect GTP from hydrolysis when the active-site histidine residue is not in position to be phosphorylated PMID: 16481318
  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    Succinate/malate CoA ligase alpha subunit family
  • 組織特異性：
    Isoform I is expressed in all tissues examined: liver, brain, heart, and skeletal muscle. Isoform II is expressed only in heart and skeletal muscle.
  • 數(shù)據(jù)庫鏈接：

    KEGG: ssc:399539

    UniGene: Ssc.14502