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Recombinant Plasmodium falciparum Fructose-bisphosphate aldolase (PF14_0425)

  • 中文名稱：
    Recombinant Plasmodium falciparum Fructose-bisphosphate aldolase(PF14_0425),Yeast
  • 貨號：
    CSB-YP762559EWP
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Plasmodium falciparum Fructose-bisphosphate aldolase(PF14_0425),Yeast
  • 貨號：
    CSB-EP762559EWP
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Plasmodium falciparum Fructose-bisphosphate aldolase(PF14_0425),Yeast
  • 貨號：
    CSB-EP762559EWP-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Plasmodium falciparum Fructose-bisphosphate aldolase(PF14_0425),Yeast
  • 貨號：
    CSB-BP762559EWP
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Plasmodium falciparum Fructose-bisphosphate aldolase(PF14_0425),Yeast
  • 貨號：
    CSB-MP762559EWP
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PF14_0425
  • Uniprot No.：
  • 別名：
    PF14_0425; Fructose-bisphosphate aldolase; EC 4.1.2.13
  • 種屬：
    Plasmodium falciparum (isolate 3D7)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-369
  • 氨基酸序列
    MAHCTEYMNA PKKLPADVAE ELATTAQKLV QAGKGILAAD ESTQTIKKRF DNIKLENTIE NRASYRDLLF GTKGLGKFIS GAILFEETLF QKNEAGVPMV NLLHNENIIP GIKVDKGLVN IPCTDEEKST QGLDGLAERC KEYYKAGARF AKWRTVLVID TAKGKPTDLS IHETAWGLAR YASICQQNRL VPIVEPEILA DGPHSIEVCA VVTQKVLSCV FKALQENGVL LEGALLKPNM VTAGYECTAK TTTQDVGFLT VRTLRRTVPP ALPGVVFLSG GQSEEEASVN LNSINALGPH PWALTFSYGR ALQASVLNTW QGKKENVAKA REVLLQRAEA NSLATYGKYK GGAGGENAGA SLYEKKYVY
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a key role in glycolysis by catalyzing the cleavage of fructose 1,6-bisphosphate into dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Independently of its catalytic activity, connects the actin filaments, and thus the actomyosin motor, to cell surface adhesins of the thrombospondin-related anonymous protein (TRAP), the erythrocyte binding ligand (EBL) and reticulocyte binding homolog (RH) protein families; this interaction is probably involved in transducing the motor force across the parasite surface required for sporozoite and ookinete gliding motility and merozoite invasion. Stimulates actin polymerisation.
  • 基因功能參考文獻(xiàn)：
    1. The molecular flexibility and the multimeric nature of aldolase are both critical for its interactions with both TRAP and actin in the invasion machinery PMID: 17426153
    2. Used a large compound library to study candidate compounds that stabilize and prevent the disassembly of the PfAldolase-TRAP complex of the glideosome. PMID: 26289816
  • 亞細(xì)胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Host cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Class I fructose-bisphosphate aldolase family
  • 數(shù)據(jù)庫鏈接：