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世界防治瘧疾日:
攜手抗“瘧”,共筑健康未來

世界防治瘧疾日

每年的4月25日是“世界防治瘧疾日”(World Malaria Day),這一天旨在喚起全球?qū)汞懠驳囊庾R,提高人們對這一疾病的認知,加強合作,推動實現(xiàn)全球瘧疾零負擔的愿景。作為全球范圍內(nèi)最為致命的傳染病之一,瘧疾每年造成全球幾十萬人的死亡,尤其對兒童和孕婦構(gòu)成嚴重威脅。因此,這一天不僅是紀念抗擊瘧疾的斗爭歷程,更是為了倡導科學進步,強化預防措施,提高診斷和治療水平。今年的主題是“防止瘧疾再傳播,持續(xù)鞏固消除成果”。

瘧疾(Malaria)是由瘧原蟲屬寄生蟲引起的一種可致命的傳染病,當攜帶瘧原蟲的雌性按蚊叮咬人體時,會將瘧原蟲的孢子體注入人體血液中,這些孢子體隨后侵入肝細胞發(fā)育成裂殖體,并進一步侵犯紅細胞,引發(fā)周期性的發(fā)熱、寒戰(zhàn)、出汗和頭痛等癥狀。按照感染人類的不同瘧原蟲種類的不同,將瘧疾分為日瘧、卵形瘧、三日瘧和惡性瘧等類型。

目前,瘧疾治療通常是根據(jù)不同類型的瘧疾針對性的選用藥物治療,無需手術。在藥物研發(fā)方面,鑒于瘧疾對傳統(tǒng)抗瘧藥物如氯喹和磺胺多辛-乙胺嘧啶等的耐藥性增加,科研人員正致力于尋找和驗證新的藥物靶點。其中,針對瘧原蟲生命周期特定階段的藥物設計受到特別關注,比如抑制瘧原蟲在肝臟期發(fā)育的藥物,或是阻止瘧原蟲在紅細胞內(nèi)繁殖的化合物。在過去的幾年里,單克隆抗體療法也展現(xiàn)出潛力,能夠特異性地結(jié)合并清除瘧原蟲,減少瘧疾的傳播和發(fā)病。

此外,瘧疾疫苗的研發(fā)一直是全球健康領域的熱點。盡管首個獲批用于兒童的RTS,S/AS01(商品名Mosquirix)瘧疾疫苗已經(jīng)在部分高風險地區(qū)投入使用,但它提供的保護效力有限且不持久。因此,科研人員正在探索更為有效的疫苗策略,包括基于蛋白質(zhì)的多表位疫苗、RNA疫苗及DNA疫苗等,力求提升疫苗誘導的免疫反應強度和持久性。

華美生物長期致力于為科研工作者提供高質(zhì)量的蛋白、抗體、ELISA試劑盒等工具類科研試劑產(chǎn)品,鑒于瘧疾研究的重要性與迫切性,在此特別整理了一系列與瘧疾研究相關的20余種熱門靶點及相關試劑產(chǎn)品列舉如下,供您選擇:

瘧疾研究相關ELISA試劑盒:

產(chǎn)品名稱 貨號 靶點 檢測范圍 靈敏度
大鼠血管緊張素轉(zhuǎn)化酶2(ACE2)酶聯(lián)免疫試劑盒 CSB-E14308r ACE2 0.02 ng/ml - 20 ng/ml 0.02 ng/ml
人血管緊張素轉(zhuǎn)化酶2(ACE2)酶聯(lián)免疫試劑盒 CSB-E04489h ACE2 0.156 ng/mL-10 ng/mL 0.039 ng/mL
小鼠血管緊張素轉(zhuǎn)化酶2(ACE2)酶聯(lián)免疫試劑盒 CSB-E17204m ACE2 6.25 pg/mL-400 pg/mL 1.56 pg/mL
人RACα絲氨酸/蘇氨酸蛋白激酶(AKT1)酶聯(lián)免疫試劑盒 CSB-EL001553HU AKT1 0.312 ng/mL-20 ng/mL 0.078 ng/mL
牛白蛋白(ALB)酶聯(lián)免疫試劑盒 CSB-E08664b ALB 0.313 μg/mL-80 μg/mL 0.148 μg/mL
小鼠白蛋白酶聯(lián)免疫試劑盒 CSB-E13878m ALB 0.781 μg/mL-200 μg/mL 0.110 μg/mL
犬白蛋白(Alb)酶聯(lián)免疫試劑盒 CSB-E15757c ALB 0.273 μg/mL-35 μg/mL 0.266 μg/mL
綿羊白蛋白酶聯(lián)免疫試劑盒 CSB-E15839Sh ALB 350 μg/mL-21.88 μg/mL 5.5 μg/mL
馬白蛋白酶聯(lián)免疫試劑盒 CSB-E16205Hs ALB 1.25 μg/mL-80 μg/mL 1.247 μg/mL
豬白蛋白酶聯(lián)免疫試劑盒 CSB-E16207p ALB 0.03 μg/mL-7000 μg/mL 0.03 μg/mL
山羊白蛋白(Alb)酶聯(lián)免疫試劑盒 CSB-E15758G ALB 0.17 μg/mL-350 μg/mL 0.17 μg/mL
豚鼠白蛋白(ALB)酶聯(lián)免疫試劑盒 CSB-E15765Gp ALB 0.156 μg/mL-10 μg/mL 0.09 μg/mL
兔白蛋白酶聯(lián)免疫試劑盒 CSB-E16204Rb ALB 0.273 μg/mL-70 μg/mL 0.117 μg/mL
人CD4分子(CD4)酶聯(lián)免疫試劑盒 CSB-E08956h CD4 0.625 ng/mL-40 ng/mL 0.156 ng/mL
大鼠CD4分子(CD4)酶聯(lián)免疫試劑盒 CSB-E12928r CD4 0.78 U/mL-50 U/mL 0.195 U/mL
雞CD4分子(CD4)酶聯(lián)免疫試劑盒 CSB-E13114C CD4 3.125 ng/mL-800 ng/mL 3.125 ng/mL
人CD8分子(CD8)酶聯(lián)免疫試劑盒 CSB-E12707h CD8A 62.5 U/mL-4000 U/mL 15.6 U/mL
小鼠C反應蛋白(CRP)酶聯(lián)免疫試劑盒 CSB-E07923m(1) CRP 5 ng/mL-4000 ng/mL 5 ng/mL
兔子C反應蛋白(CRP)酶聯(lián)免疫試劑盒 CSB-E06847Rb CRP 7.8 pg/mL-2000 pg/mL 2 pg/mL
大鼠C反應蛋白(CRP)酶聯(lián)免疫試劑盒 CSB-E07922r CRP 31.25 ng/mL-2000 ng/mL 7.81 ng/mL

瘧疾研究相關重組蛋白:

產(chǎn)品名稱 貨號 靶點 來源 蛋白標簽
Recombinant Mouse Serum albumin (Alb) CSB-BP001561MO Alb Baculovirus C-terminal 9xHis-tagged
Recombinant Macaca mulatta Interleukin-10 (IL10) CSB-BP011580MOW IL10 Baculovirus N-terminal 10xHis-tagged and C-terminal myc-tagged
Recombinant Macaca mulatta Interleukin-10 (IL10) CSB-BP011580MOWd7 IL10 Baculovirus C-terminal 10xHis-tagged
Recombinant Marmota monax Tumor necrosis factor (TNF), partial CSB-BP523593MQG TNF Baculovirus N-terminal 10xHis-tagged
Recombinant Human T-cell surface glycoprotein CD4 (CD4), partial CSB-CF004935HU1 CD4 in vitro E.coli expression system N-terminal 6xHis-tagged
Recombinant Human RAC-alpha serine/threonine-protein kinase (AKT1) CSB-EP001553HU AKT1 E.coli N-terminal GST-tagged
Recombinant Dog Serum albumin (ALB) CSB-EP001561DO ALB E.coli N-terminal 6xHis-tagged
Recombinant Macaca fascicularis albumin (ALB) CSB-EP001561MOV ALB E.coli N-terminal 6xHis-SUMO-tagged
Recombinant Bovine T-cell surface glycoprotein CD8 alpha chain (CD8A), partial CSB-EP004966BO CD8A E.coli N-terminal 6xHis-SUMO-tagged
Recombinant Human T-cell surface glycoprotein CD8 alpha chain (CD8A), partial CSB-EP004966HU CD8A E.coli N-terminal 6xHis-SUMO-tagged
Recombinant Human Epidermal growth factor receptor (EGFR), partial CSB-EP007479HU3 EGFR E.coli N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
Recombinant Human Receptor tyrosine-protein kinase erbB-2 (ERBB2), partial CSB-EP007763HU ERBB2 E.coli N-terminal 6xHis-tagged
Recombinant Human Receptor tyrosine-protein kinase erbB-2 (ERBB2), partial CSB-EP007763HU1 ERBB2 E.coli N-terminal 6xHis-tagged
Recombinant Human Receptor tyrosine-protein kinase erbB-2 (ERBB2), partial CSB-EP007763HU3 ERBB2 E.coli N-terminal 10xHis-tagged and C-terminal Myc-tagged
Recombinant Human Alanine aminotransferase 1 (GPT) CSB-EP009864HU GPT E.coli N-terminal 6xHis-tagged
Recombinant Chicken Interferon gamma (IFNG) CSB-EP011050CH IFNG E.coli N-terminal GST-tagged
Recombinant Human Interferon gamma (IFNG) CSB-EP011050HU IFNG E.coli N-terminal 6xHis-tagged
Recombinant Mouse Interferon gamma (Ifng), partial CSB-EP011050MO1 Ifng E.coli N-terminal 6xHis-tagged
Recombinant Marmota monax Interferon gamma (IFNG) CSB-EP011050MQG IFNG E.coli N-terminal 6xHis-tagged
Recombinant Rat Interferon gamma (Ifng) CSB-EP011050RA Ifng E.coli N-terminal GST-tagged

瘧疾研究相關抗體:

● 重組抗體:

產(chǎn)品名稱 貨號 靶點 反應種屬 應用范圍
Phospho-AKT1 (T450) Recombinant Monoclonal Antibody CSB-RA001553A450phHU AKT1 Human ELISA, WB
Phospho-AKT1 (Ser473) Recombinant Monoclonal Antibody CSB-RA001553A473phHU AKT1 Human ELISA, WB, IHC, IF, IP
AKT1 Recombinant Monoclonal Antibody CSB-RA917625A0HU AKT1 Human, Mouse, Rat ELISA, WB, IHC, IF
ALB Recombinant Monoclonal Antibody CSB-RA264109A0HU ALB Human ELISA, FC
CD4 Recombinant Monoclonal Antibody CSB-RA004935A0HU CD4 Human ELISA, WB, IHC
CD8A Recombinant Monoclonal Antibody CSB-RA934881A0HU CD8A Human ELISA, WB, IHC, IP
CRP Recombinant Monoclonal Antibody CSB-RA988767A0HU CRP Human ELISA, IHC
Phospho-EGFR (Y1092) Recombinant Monoclonal Antibody CSB-RA007479A1092phHU EGFR Human ELISA, WB
Phospho-EGFR (Y1068) Recombinant Monoclonal Antibody CSB-RA007479A1068phHU EGFR Human ELISA, WB
EGFR Recombinant Monoclonal Antibody CSB-RA159341A0HU EGFR Human ELISA, WB, IHC, IF, FC
EGFR Recombinant Monoclonal Antibody CSB-RA794061A0HU EGFR Human ELISA, WB, IHC
EGFR Recombinant Monoclonal Antibody CSB-RA159341MA1HU EGFR Human ELISA, IHC, FC
ERBB2 Recombinant Monoclonal Antibody CSB-RA260392A0HU ERBB2 Human ELISA, IHC, IF
ERBB2 Recombinant Monoclonal Antibody CSB-RA007763MA1HU ERBB2 Human ELISA
Phospho-ERBB2 (Y1139) Recombinant Monoclonal Antibody CSB-RA588766A0HU ERBB2 Human ELISA, IHC, IF
ERBB2 Recombinant Monoclonal Antibody CSB-RA007763MA2HU ERBB2 Human ELISA, IHC
IL10 Recombinant Monoclonal Antibody CSB-RA011580A0HU IL10 Human ELISA
IL6 Recombinant Monoclonal Antibody CSB-RA011664MA1HU IL6 Human ELISA
INS Recombinant Monoclonal Antibody CSB-RA584163A0HU INS Human ELISA, IHC
Phospho-MTOR (S2481) Recombinant Monoclonal Antibody CSB-RA008968A2481phHU MTOR Human ELISA, WB, IF
Phospho-MTOR (S2448) Recombinant Monoclonal Antibody CSB-RA008968A2448phHU MTOR Human ELISA, WB, IHC, IF

● 單克隆抗體:

產(chǎn)品名稱 貨號 靶點 反應種屬 應用范圍
AKT1 Monoclonal Antibody CSB-MA011037 AKT1 Human,Mouse,Pig,Rat ELISA, WB
ALB Monoclonal Antibody CSB-MA076752 ALB Human ELISA, WB, IHC
CD4 Monoclonal Antibody CSB-MA000228 CD4 Human,Mouse,Rat ELISA, IHC
CD4 Monoclonal Antibody,Purified CSB-MA783233 CD4 Human ELISA, FC
CD8A Monoclonal Antibody,Purified CSB-MA927984 CD8A Human ELISA, FC
CRP Monoclonal Antibody CSB-MA027411E0m CRP Human ELISA, IHC
CXCL8 Monoclonal Antibody CSB-MA083271A0m CXCL8 Human ELISA, IHC
EGFR Monoclonal Antibody CSB-MA000199 EGFR Human ELISA, WB, IHC, IF
EGFR Monoclonal Antibody CSB-MA000293 EGFR Human ELISA, WB
ERBB2 Monoclonal Antibody CSB-MA000200 ERBB2 Human,Mouse,Rat ELISA, WB, IHC
ERBB2 Monoclonal Antibody CSB-MA000237 ERBB2 Human ELISA, WB
ERBB2 Monoclonal Antibody CSB-MA172796 ERBB2 Human ELISA, WB, IHC
IFNG Monoclonal Antibody CSB-MA065241A0m IFNG Human ELISA, IHC
IL6 Monoclonal Antibody CSB-MA067571A0m IL6 Human ELISA, WB, IHC
TNF Monoclonal Antibody CSB-MA084771A0m TNF Bovine ELISA
TNF Monoclonal Antibody CSB-MA080271 TNF Human,Mouse,Rat ELISA, WB, IHC
TNF Monoclonal Antibody CSB-MA080272 TNF Human,Mouse,Rat ELISA, WB, IHC

● 多克隆抗體:

產(chǎn)品名稱 貨號 靶點 反應種屬 應用范圍
ACE2 Antibody CSB-PA866317LA01HU ACE2 Human ELISA, IHC, IF
Ace2 Antibody CSB-PA688690OA01RA Ace2 Rat ELISA, WB
ACE2 Antibody CSB-PA040178 ACE2 Human, Mouse ELISA, WB
ACE2 Antibody CSB-PA001150GA01HU ACE2 Human, Mouse, Rat ELISA, WB
ACE2 Antibody CSB-PA111496 ACE2 Human ELISA, IHC
ACE2 Antibody CSB-PA025395 ACE2 Human, Mouse, Rat ELISA, IHC
ACE2 Antibody CSB-PA445794 ACE2 Human, Mouse, Rat ELISA, IHC
AKT1 Antibody CSB-PA15905A0Rb AKT1 Human ELISA, WB, IHC, IF, IP
AKT1 Antibody CSB-PA000852 AKT1 Human, Mouse, Rat ELISA, WB, IHC, IF
Phospho-AKT1 (S124) Antibody CSB-PA008118 AKT1 Human, Mouse, Rat ELISA, WB, IHC
Phospho-AKT1 (T72) Antibody CSB-PA008120 AKT1 Human, Mouse, Rat ELISA, WB, IHC
AKT1 Antibody CSB-PA008122 AKT1 Human, Mouse, Rat ELISA, IHC
AKT1 Antibody CSB-PA080256 AKT1 Human, Mouse, Rat WB
Phospho-AKT1 (S129) Antibody CSB-PA000645 AKT1 Human, Mouse, Rat ELISA, WB
Phospho-AKT1 (T308) Antibody CSB-PA000657 AKT1 Human, Mouse, Rat ELISA, WB
Phospho-AKT1 (S473) Antibody CSB-PA000732 AKT1 Human, Mouse, Rat ELISA, WB, IHC, IF
AKT1 Antibody CSB-PA000851 AKT1 Human, Mouse, Rat, Monkey ELISA, WB, IHC, IF
Phospho-AKT1 (S246) Antibody CSB-PA000465 AKT1 Human, Mouse, Rat ELISA, WB, IHC, IF
Phospho-AKT1 (T450) Antibody CSB-PA000468 AKT1 Human, Mouse, Rat ELISA, WB, IHC
Phospho-AKT1 (Y326) Antibody CSB-PA000649 AKT1 Human, Mouse, Rat ELISA, WB