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CDC42

Cell division control protein 42 homolog, also known as Cdc42, is a protein involved in regulation of the cell cycle. Human Cdc42 is a small GTPase of the Rho family, which regulates signaling pathways that control diverse cellular functions including cell morphology, cell migration, endocytosis and cell cycle progression.. Rho GTPases are central to dynamic actin cytoskeletal assembly and rearrangement that are the basis of cell-cell adhesion and migration. Activated Cdc42 activates by conformational changes p21-activated kinases PAK1 and PAK2, which in turn initiate actin reorganization and regulate cell adhesion, migration, and invasion.

CDC42 Antibodies

CDC42 for Homo sapiens (Human)

CDC42 Proteins

CDC42 Proteins for Mus musculus (Mouse)

CDC42 Proteins for Homo sapiens (Human)

CDC42 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CDC42 Proteins for Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

CDC42 Proteins for Candida albicans (strain WO-1) (Yeast)

CDC42 Proteins for Colletotrichum gloeosporioides (Anthracnose fungus) (Glomerella cingulata)

CDC42 Proteins for Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

CDC42 Proteins for Drosophila melanogaster (Fruit fly)

CDC42 Proteins for Anopheles gambiae (African malaria mosquito)

CDC42 Proteins for Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

CDC42 Proteins for Drosophila pseudoobscura pseudoobscura (Fruit fly)

CDC42 Proteins for Bos taurus (Bovine)

CDC42 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

CDC42 Proteins for Rattus norvegicus (Rat)

CDC42 Proteins for Gallus gallus (Chicken)

CDC42 Proteins for Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)