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CLU

CLU,即叢生蛋白,別名SGP-2、SP-40、TRPM-2、KUB1、CLU1、CLU2。CLU是一種高度保守的糖蛋白,屬于補(bǔ)體系統(tǒng)調(diào)節(jié)因子和受體家族,廣泛分布于不同物種中。CLU的作用機(jī)制涉及多種生物學(xué)功能,包括調(diào)節(jié)細(xì)胞凋亡、促進(jìn)細(xì)胞聚集、組織修復(fù)、轉(zhuǎn)運(yùn)脂類、補(bǔ)體抑制和免疫調(diào)節(jié)。CLU可以編碼不同的蛋白產(chǎn)物,具有不同的細(xì)胞定位,發(fā)揮不同的生物學(xué)功能,主要是分泌型(sCLU)及核型(nCLU)。CLU不僅與多種生物過(guò)程相關(guān),而且還與多種病理狀態(tài)有關(guān),如神經(jīng)退行性疾病、衰老和癌癥。CLU的表達(dá)與多種疾病的發(fā)生發(fā)展相關(guān),使其成為一個(gè)有潛力的治療靶點(diǎn)和生物標(biāo)志物。

熱銷產(chǎn)品

Recombinant Human Clusterin (CLU) (CSB-MP005595HU)

驗(yàn)證數(shù)據(jù)

CSB-MP005595HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CLU Recombinant Monoclonal Antibody (CSB-RA449834A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA449834A0HU

IHC image of CSB-RA449834A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CSB-RA449834A0HU

IHC image of CSB-RA449834A0HU diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CLU Antibodies

CLU for Homo sapiens (Human)

CLU Proteins

CLU Proteins for Homo sapiens (Human)

CLU Proteins for Ovis aries (Sheep)

CLU Proteins for Bos taurus (Bovine)

CLU Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CLU Proteins for Mesocricetus auratus (Golden hamster)

CLU Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)

CLU Proteins for Rattus norvegicus (Rat)

CLU Proteins for Drosophila melanogaster (Fruit fly)

CLU Proteins for Drosophila ananassae (Fruit fly)

CLU Proteins for Drosophila virilis (Fruit fly)

CLU Proteins for Drosophila yakuba (Fruit fly)

CLU Proteins for Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)

CLU Proteins for Drosophila willistoni (Fruit fly)

CLU Proteins for Drosophila erecta (Fruit fly)

CLU Proteins for Drosophila mojavensis (Fruit fly)

CLU Proteins for Drosophila persimilis (Fruit fly)

CLU Proteins for Oryctolagus cuniculus (Rabbit)

CLU Proteins for Sus scrofa (Pig)

CLU Proteins for Equus caballus (Horse)

CLU Proteins for Drosophila pseudoobscura pseudoobscura (Fruit fly)

CLU ELISA Kit

CLU ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

CLU ELISA Kit for Equus caballus (Horse)

CLU ELISA Kit for Homo sapiens (Human)

CLU ELISA Kit for Mus musculus (Mouse)