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GH1

生長激素-不僅僅促進(jìn)長高

生長激素1(growth hormone 1,GH1)也被稱為垂體生長激素,或簡單地稱為生長激素(GH),是生長激素/催乳激素家族中的一員。人類基因組包含5個GH相關(guān)基因:人生長激素(hGH)、人類絨毛膜生長催乳素-A(hCS-A)、人類絨毛膜生長催乳素-B(hCS-B)、人類絨毛膜生長催乳激素類似物(hCS-L)、人類生長素變異體(hGH-V)。它們是一類由腦垂體前葉嗜酸性顆粒的生長激素分泌細(xì)胞分泌的一種單一肽鏈的蛋白質(zhì)激素,其主要作用是促進(jìn)生長發(fā)育和影響代謝。此外,研究表明生長激素對神經(jīng)系統(tǒng)疾病也具有較廣泛的生理作用,特別是在神經(jīng)修復(fù)和神經(jīng)保護(hù)方面有比較大的作用。GH1基因的突變或缺失會導(dǎo)致生長激素缺乏和身材矮小。另有報道指出GH1/IGF-1途徑在癌癥的發(fā)生和發(fā)展過程中起到了重要的作用,GH1/IGF-1水平升高與食管癌以及大腸癌的發(fā)病風(fēng)險顯著關(guān)聯(lián)。

Recombinant Human GH1 活性蛋白實驗驗證數(shù)據(jù)

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Measured by its binding ability in a functional ELISA. Immobilized human GH1 at 2 μg/ml can bind Biotinylated human GHR (CSB-MP009411HUj1-B), the EC50 is 2.067-3.208 ng/ml.

Excellent Bioactivity Validated by LSPR Assay

Human GH1 protein his/myc tag (CSB-MP009407HU) captured on COOH chip can bind Human GHR protein Fc tag (CSB-MP009411HU) with an affinity constant of 6.1 nM as detected by LSPR Assay.


GH1 Antibodies

GH1 for Homo sapiens (Human)

GH1 Proteins

GH1 Proteins for Capra hircus (Goat)

GH1 Proteins for Ovis aries (Sheep)

GH1 Proteins for Macaca mulatta (Rhesus macaque)

GH1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

GH1 Proteins for Felis catus (Cat) (Felis silvestris catus)

GH1 Proteins for Oryctolagus cuniculus (Rabbit)

GH1 Proteins for Bos taurus (Bovine)

GH1 Proteins for Mus musculus (Mouse)

GH1 Proteins for Sus scrofa (Pig)

GH1 Proteins for Equus caballus (Horse)

GH1 Proteins for Vulpes vulpes (Red fox)

GH1 Proteins for Mustela vison (American mink) (Neovison vison)

GH1 Proteins for Loxodonta africana (African elephant)

GH1 Proteins for Mesocricetus auratus (Golden hamster)

GH1 Proteins for Lama guanicoe pacos (Alpaca) (Lama pacos)

GH1 Proteins for Balaenoptera borealis (Sei whale) (Pollack whale)

GH1 Proteins for Saimiri boliviensis boliviensis (Bolivian squirrel monkey)

GH1 Proteins for Cervus elaphus (Red deer)

GH1 Proteins for Pan troglodytes (Chimpanzee)

GH1 Proteins for Rattus norvegicus (Rat)

GH1 Proteins for Bubalus bubalis (Domestic water buffalo)

GH1 Proteins for Trichosurus vulpecula (Brush-tailed possum)

GH1 Proteins for Spalax ehrenbergi (Middle East blind mole rat) (Nannospalax ehrenbergi)

GH1 Proteins for Acipenser guldenstadti (Caspian sturgeon) (Russian sturgeon)

GH1 Proteins for Anguilla japonica (Japanese eel)

GH1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

GH1 Proteins for Carassius auratus (Goldfish)

GH1 Proteins for Bos gaurus frontalis (Domestic gayal) (Bos frontalis)

GH1 Proteins for Balaenoptera physalus (Finback whale) (Common rorqual)

GH1 Proteins for Bos mutus grunniens (Wild yak) (Bos grunniens)

GH1 Proteins for Camelus dromedarius (Dromedary) (Arabian camel)

GH1 Proteins for Ailuropoda melanoleuca (Giant panda)

GH1 Proteins for Delphinus delphis (Saddleback dolphin) (Black sea dolphin)

GH1 Proteins for Oncorhynchus nerka (Sockeye salmon) (Salmo nerka)

GH1 Proteins for Callithrix jacchus (White-tufted-ear marmoset)

GH1 Proteins for Monodelphis domestica (Gray short-tailed opossum)

GH1 Proteins for Cavia porcellus (Guinea pig)

GH1 Proteins for Galago senegalensis (Northern lesser bushbaby) (Senegal bushbaby)

GH1 Proteins for Nycticebus pygmaeus (Pygmy slow loris)

GH1 Proteins for Homo sapiens (Human)

GH1 ELISA Kit

GH1 ELISA Kit for Fish

GH1 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

GH1 ELISA Kit for Capra hircus (Goat)

GH1 ELISA Kit for Equus caballus (Horse)

GH1 ELISA Kit for Monkey

GH1 ELISA Kit for Mus musculus (Mouse)

GH1 ELISA Kit for Ovis aries (Sheep)

GH1 ELISA Kit for Bos taurus (Bovine)

GH1 ELISA Kit for Oryctolagus cuniculus (Rabbit)

GH1 ELISA Kit for Sus scrofa (Pig)