Your Good Partner in Biology Research

先天性遺傳性新生兒疾病和畸形

先天性遺傳性新生兒疾病和畸形是由遺傳因素引起的新生兒健康問題,這些疾病可能在出生時或生后的早期就已經(jīng)存在。包括代謝性疾病、血液疾病、先天性心臟病、神經(jīng)管缺陷等。

目前,先天性遺傳性新生兒疾病和畸形的藥物研發(fā)正在積極探索當中,主要集中在以下幾個方向:

  • 基因治療:基因療法是針對遺傳性疾病的一種治療方法,通過替換、修復或調(diào)控致病基因來治療疾病。例如,針對先天性黑矇(一種遺傳性視網(wǎng)膜疾病)的基因治療研究正在進行,旨在通過基因療法恢復受損的視網(wǎng)膜功能。
  • 代謝性疾病治療:對于代謝性疾病,研發(fā)的新藥可能針對特定的代謝途徑,如針對PKU的治療方法,除了傳統(tǒng)的飲食控制外,正在研究能夠改善代謝途徑的藥物。
  • 新生兒疾病篩查技術(shù):隨著串聯(lián)質(zhì)譜技術(shù)(MS/MS)和基因檢測技術(shù)的發(fā)展,新生兒疾病篩查變得更加高效和準確,有助于早期診斷和干預。

先天性遺傳性新生兒疾病和畸形靶點相關(guān)產(chǎn)品推薦

● 靶點蛋白

CSB-MP009411HU Activity Verified

Human GH1 protein his/myc tag (CSB-MP009407HU) captured on COOH chip can bind Human GHR protein Fc tag (CSB-MP009411HU) with an affinity constant of 6.1 nM as detected by LSPR Assay.

CSB-MP011661HU2-B Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized Human IL4 (CSB-MP011659HU) at 2μg/mL can bind biotinylated Human IL4R,the EC50 is 12.68-14.23 ng/mL.

CSB-MP023437HU Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized Human TFPI at 1 μg/ml can bind Anti-TFPI recombinant antibody (CSB-RA023437MA01HU), the EC50 is 1.242-1.788 ng/mL.

CSB-MP619964HU1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized PD-1 at 2 μg/ml can bind Anti-PD-1 recombinant antibody, the EC50 of human PD-1 protein is 6.087-7.854 ng/ml.

CSB-MP3648HU Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized Human TFRC at 2μg/mL can bind Anti-TFRC recombinant antibody (CSB-RA023441MA1HU), the EC50 is 3.305-8.220 ng/mL.

CSB-MP009514HUb1 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized Human GLP1R at 2 μg/mL can bind Anti-GLP1R recombinant antibody (CSB-RA009514MA1HU), the EC50 is 54.54-94.23 ng/mL.

CSB-MP011649HU3 Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized Human IL2RA at 2μg/mL can bind Anti-IL2RA recombinant antibody (CSB-RA011649MA1HU),the EC50 is 2.463-3.353 ng/mL.

CSB-MP733578HU Activity Verified

Measured by its binding ability in a functional ELISA. Immobilized CD276 at 2 μg/ml can bind Anti-CD276 rabbit monoclonal antibody, the EC50 of human CD276 protein is 1.961-2.243 ng/ml.

產(chǎn)品名稱 貨號 靶點 來源 蛋白標簽
Recombinant Human ATP-binding cassette sub-family D member 1 (ABCD1) (Active) CSB-CF001068HU ABCD1 in vitro E.coli expression system C-terminal 10xHis-tagged
Recombinant Human CD276 antigen (CD276), partial (Active) CSB-MP733578HU CD276 Mammalian cell C-terminal hFc-Myc-tagged
Recombinant Human CD40 ligand (CD40LG), partial (Active) CSB-AP005191HU CD40LG E.coli Tag-Free
Recombinant Human CD40 ligand (CD40LG), partial (Active) CSB-MP004937HU3 CD40LG Mammalian cell N-terminal hFc-Flag-tagged
Recombinant Human Granulocyte-macrophage colony-stimulating factor (CSF2) (Active) CSB-AP003581HU CSF2 E.coli Tag-Free
Recombinant Human Granulocyte-macrophage colony-stimulating factor (CSF2) (Active) CSB-AP003601HU CSF2 Mammalian cell C-terminal 6xHis-tagged
Recombinant Mouse Granulocyte-macrophage colony-stimulating factor (Csf2) (Active) CSB-AP003651MO Csf2 Mammalian cell C-terminal 6xHis-tagged
Recombinant Mouse Granulocyte-macrophage colony-stimulating factor (Csf2) (Active) CSB-AP003661MO Csf2 E.coli Tag-Free
Recombinant Human Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (CSF2RA), partial (Active) CSB-AP003591HU CSF2RA Mammalian cell C-terminal 6xHis-tagged
Recombinant Human Fibroblast growth factor receptor 3 (FGFR3), partial (Active) CSB-AP003871HU FGFR3 Mammalian cell C-terminal Fc-tagged
Recombinant Human Growth hormone receptor (GHR), partial (Active) CSB-MP009411HU GHR Mammalian cell C-terminal hFc-tagged
Recombinant Human Growth hormone receptor (GHR), partial, Biotinylated (Active) CSB-MP009411HUj1-B GHR Mammalian cell C-terminal mFc-Avi-tagged
Recombinant Human Glucagon-like peptide 1 receptor (GLP1R), partial (Active) CSB-MP009514HUb1 GLP1R Mammalian cell N-terminal 10xHis-tagged and C-terminal Myc-tagged
Recombinant Rhesus Macaque Interleukin-13 protein (IL13) (Active) CSB-AP003181MOW IL13 E.Coli Tag-Free
Recombinant Human Interleukin-13 (IL13), partial (Active) CSB-AP004321HU IL13 Mammalian cell C-terminal 6xHis-tagged
Recombinant Mouse Interleukin-13 (Il13), partial (Active) CSB-AP004751MO Il13 Mammalian cell C-terminal 6xHis-tagged
Recombinant Mouse Interleukin-13 (Il13), partial (Active) CSB-AP004761MO Il13 Mammalian cell C-terminal 6xHis-tagged
Recombinant Mouse Interleukin-13 (Il13), partial (Active) CSB-AP004771MO Il13 E.coli Tag-Free
Recombinant Human Interleukin-17A (IL17A) (Active) CSB-AP004331HU IL17A E.coli Tag-Free
Recombinant Human Interleukin-17A (IL17A) (Active) CSB-AP004341HU IL17A Mammalian cell C-terminal 6xHis-tagged

● 重組抗體

IGF1R Recombinant Monoclonal Antibody
CSB-RA011087MA1HU
CSB-RA011087MA1HU FC

Overlay Peak curve showing Hela cells surface stained with CSB-RA011087MA1HU (red line) at 1:50.

RHD Recombinant Monoclonal Antibody
CSB-RA019677MA1HU
CSB-RA019677MA1HU FC

Overlay Peak curve showing Hela cells surface stained with CSB-RA019677MA1HU (red line) at 1:100.

IL1R1 Recombinant Monoclonal Antibody
CSB-RA011621MA1HU
CSB-RA011621MA1HU FC

Overlay Peak curve showing NIH/3T3 cells surface stained with CSB-RA011621MA1HU (red line) at 1:50.

C5 Recombinant Monoclonal Antibody
CSB-RA003995MA1HU
CSB-RA003995MA1HU FC

Overlay Peak curve showing Hela cells surface stained with CSB-RA003995MA1HU (red line) at 1:800.

產(chǎn)品名稱 貨號 靶點 反應種屬 應用范圍
ALB Recombinant Monoclonal Antibody CSB-RA264109A0HU ALB Human ELISA, FC
APP Recombinant Monoclonal Antibody CSB-RA994273A0HU APP Human, Mouse, Rat ELISA, WB, IF
C5 Recombinant Monoclonal Antibody CSB-RA003995MA1HU C5 Human ELISA, FC
CD247 Recombinant Monoclonal Antibody CSB-RA244537A0HU CD247 Human ELISA, FC
CD34 Recombinant Monoclonal Antibody CSB-RA004926A0HU CD34 Human ELISA, IHC
DMD Recombinant Monoclonal Antibody CSB-RA271553A0HU DMD Human ELISA, IHC
ELANE Recombinant Monoclonal Antibody CSB-RA200985A0HU ELANE Human ELISA, IHC, FC
F10 Recombinant Monoclonal Antibody CSB-RA599469A0HU F10 Human ELISA, IHC
F9 Recombinant Monoclonal Antibody CSB-RA923075A0HU F9 Human ELISA, WB
FGFR3 Recombinant Monoclonal Antibody CSB-RA555849A0HU FGFR3 Human ELISA, IF
FGFR3 Recombinant Monoclonal Antibody CSB-RA966627A0HU FGFR3 Human ELISA, WB
GAA Recombinant Monoclonal Antibody CSB-RA566370A0HU GAA Human ELISA, IHC
GHR Recombinant Monoclonal Antibody CSB-RA978909A0HU GHR Human ELISA, IHC, IF
GLP1R Recombinant Monoclonal Antibody CSB-RA009514MA1HU GLP1R Human ELISA
IFNAR1 Recombinant Monoclonal Antibody CSB-RA011046A0HU IFNAR1 Human ELISA
IGF1R Recombinant Monoclonal Antibody CSB-RA011087MA1HU IGF1R Human ELISA, FC
IL17A Recombinant Monoclonal Antibody CSB-RA624104MA1HU IL17A Human ELISA
IL1R1 Recombinant Monoclonal Antibody CSB-RA011621MA1HU IL1R1 Human ELISA, FC
IL2RA Recombinant Monoclonal Antibody CSB-RA011649MA1HU IL2RA Human ELISA, IF
IL4 Recombinant Monoclonal Antibody CSB-RA240377A0HU IL4 Human ELISA, IHC

● ELISA試劑盒

產(chǎn)品名稱 貨號 靶點 檢測范圍 靈敏度
Bovine Albumin(Alb) ELISA kit CSB-E08664b ALB 0.313 μg/mL-80 μg/mL 0.148 μg/mL
Mouse Albumin (Alb)ELISA Kit CSB-E13878m ALB 0.781 μg/mL-200 μg/mL 0.110 μg/mL
Dog Albumin(Alb) ELISA Kit CSB-E15757c ALB 0.273 μg/mL-35 μg/mL 0.266 μg/mL
Sheep Albumin (Alb)ELISA Kit CSB-E15839Sh ALB 350 μg/mL-21.88 μg/mL 5.5 μg/mL
Horse Albumin(Alb) ELISA Kit CSB-E16205Hs ALB 1.25 μg/mL-80 μg/mL 1.247 μg/mL
Pig Albumin (Alb) ELISA Kit CSB-E16207p ALB 0.03 μg/mL-7000 μg/mL 0.03 μg/mL
Goat Albumin (Alb)ELISA Kit CSB-E15758G ALB 0.17 μg/mL-350 μg/mL 0.17 μg/mL
Guinea Pig Albumin(Alb) ELISA kit CSB-E15765Gp ALB 0.156 μg/mL-10 μg/mL 0.09 μg/mL
Rabbit Albumin(Alb) ELISA Kit CSB-E16204Rb ALB 0.273 μg/mL-70 μg/mL 0.117 μg/mL
Human angiopoietin-like protein 3,ANGPTL3 ELISA Kit CSB-E11724h ANGPTL3 78 pg/mL-5000 pg/mL 19.5 pg/mL
Mouse Angiopoietin-related protein 3(ANGPTL3) ELISA kit CSB-EL001711MO ANGPTL3 31.25 pg/mL-2000 pg/mL 10.24 pg/mL
Human apolipoprotein A1 (Apo-A1) ELISA Kit CSB-E08103h APOA1 1.4 ng/mL-1000 ng/mL 0.7 ng/mL
Rat apolipoprotein A1 (Apo-A1) ELISA Kit CSB-E08105r APOA1 0.14 ng/ml-100 ng/ml. 0.14 ng/ml.
Pig apolipoprotein A1 (Apo-A1) ELISA Kit CSB-E06834p APOA1 80 μg/mL-2000 μg/mL 50 μg/mL
Mouse apolipoprotein A1(Apo-A1) ELISA Kit CSB-E08104m APOA1 31.25 ng/mL-2000 ng/mL 7.81 ng/mL
Rabbit apolipoprotein A1 (Apo-A1) ELISA Kit CSB-E09804Rb APOA1 6.25 μg/mL-400 μg/mL 1.56 μg/mL
Bovine Apolipoprotein A-I(APOA1) ELISA kit CSB-EL001913BO APOA1 78 ng/mL-5000 ng/mL 19.5 ng/mL
Dog Apolipoprotein A-I(APOA1) ELISA kit CSB-EL001913DO APOA1 28.12 ng/mL-1800 ng/mL 7 ng/mL
Rat Amyloid beta A4 protein(APP) ELISA kit CSB-EL001950RA APP 15.6 ng/mL-1000 ng/mL 3.9 ng/mL
Human Complement C1s subcomponent(C1S) ELISA kit CSB-EL003657HU C1S 25 ng/mL-1600 ng/mL 6.25 ng/mL